Metformin Case
Question / Problem: What is the evidence to recommend Trulicity (dulaglutide) to a patient who has uncontrolled glucose control, and is on metformin and insulin (levemir) and non- adherence to the insulin.
Response: The trulicity is a non-insulin injectable with dosing regimen of once weekly dosing. These agents work by activating GLP-1 receptors in the pancreas, which leads to enhanced insulin release and reduced glucagon release-responses that are both glucose-dependent-with a consequent low risk for hypoglycemia. Effects on GLP-1 receptors in the CNS and the gastrointestinal tract cause reduced appetite and delayed glucose absorption due to slower gastric emptying.1 Dulaglutide 1.5 mg and 0.75 mg is studied in patients is age groups of age > 65 and < 65 years to achieve the HbA1c target of <7% ranged from 53 to 78% for dulaglutide 1.5 mg and from 37 to
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In the dulaglutide 1.5 mg change in body weight was from 0.9-3.0 kg and 0.2-2.6 kg for dulaglutide 0.75 mg. 2 One of the study conducted in Hispanic/Latino patients receiving dulaglutide 1.5 and 0.75 mg to see the reduction in HbA1c. Hispanic/Latino patients receiving dulaglutide 1.5 mg had a reduction in HbA1c of 1.25%, and dulaglutide 0.75 mg had a reduction of 1.07%. Dulaglutide improved glycemic control with the potential for weight loss in Hispanic/Latino patients with T2D. Dulaglutide was well tolerated and had a low risk of hypoglycemia when used without insulin secretagogues or insulin.3 Dulaglutide is available as a single-dose automatic self-injecting device, which has a low volume, does not need reconstitution, and avoids patient handling of the needle. No dose adjustment requires based on weight, sex, age,
Facilitated Diffusion Case Study
1020 Words | 5 PagesThe supply of glucose to the brain and immune system is important as competitors constantly rely on instantaneous decision making to ensure they make effective strategic moves. Glucagon is the hormone which ultimately increases blood glucose concentration by breaking down stored glycogen in muscle and fat cells, increasing the breakdown of fats and increasing liver glucose production. Each of these effects lead to an increased amount of glucose present in the bloodstream, meaning more energy for body cells. When the level of glucose in the bloodstream drops, more glucose is required in order to provide ATP for energy. The secretion of insulin by beta cells is inhibited
Methkein Case Summary
243 Words | 1 PagesMILLERSBURG — For the second time in recent history, a man convicted of making meth has withdrawn a long-ago guilty plea in an attempt to remedy a issue created by a recent Supreme Court decision, which defeated the initial intent of his original sentence. Troy Lastohkein, 49, who has been serving an eight-year sentence at Richland Correctional Institution, sat Thursday in the Common Pleas Court Judge Robert Rinfret's courtroom. There he withdrew his initial guilty plea to felony charges of illegal assembly of chemicals to manufacture methamphetamine, child endangering and drug trafficking. He immediately pleaded guilty to similar charges, which limit the mandatory time he is required to serve before being eligible for early release.
Compound 17392
691 Words | 3 PagesAn endocrinologist who practiced in New York City, Dr. Carlos Carera, was invited to attend the two-day protocol meeting to introduce the phase four clinical trial. He was interested in the development and research since some of his patients either could not tolerate or weren’t doing well on the available drugs for diabetes. Dr. Carera’s goal seems to involve participating in research to evolve and improve drugs for type-two diabetes and to be able to benefit his patients.
Elizabeth Horton Case Study
491 Words | 2 PagesElizabeth Horton is 69 year old female. She has a history of colon resection, with ostomy bag, iron deficiency anemia, lactose intolerance, diverticulitis and constipation. Mrs. Horton has no known drug allergies and is prescribed a regular diet. Previous diets have consisted of NPO, clear liquid diet, TPN with liquids to a regular diet. Mrs. Horton’s eating habits consisted of eating a wide variety of snacks during the day.
Annotated Bibliography: Lancet Glob Health
382 Words | 2 PagesJAMA Intern Med, 173, 1328-35. Ripsin, C. M., H. Kang & R. J. Urban (2009) Management of blood glucose in type 2 diabetes mellitus. Am Fam Physician, 79, 29-36. Willi, C., P. Bodenmann, W. A. Ghali, P. D. Faris & J. Cornuz (2007) Active smoking and the risk of type 2 diabetes: a systematic review and meta-analysis.
Pros And Cons Of Vedda Blood Sugar Remedy
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Diabetes 60 System Research Paper
460 Words | 2 PagesDiabetes 60 System Review - Dr Shelton System Legit? You’re here probably because you heard people talking about the diabetes 60 System, or just because you want to know more about how Dr Shelton System works. Whichever your reason is, this short review will reveal more information about the diabetes 60 system, the efficacy, and what people are saying about it.
Tegaserod Case Study
433 Words | 2 PagesTegaserod was shown to provide rapid, predictable, and consistent relief of chronic constipation.1 Additionally, only 1 percent of patients experienced significant adverse events but none of them were found to be attributable to the use of Tegaserod.1 In March 2007, the drug was pulled
Type II Diabetes Case Study
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High Cholesterol Familial Homozygous Case Study
383 Words | 2 PagesAnd it also used to treat mixed dislipidaemia and which abnormal levels of fats in blood including high levels of LDL cholesterol.
Ondansetron Case Study
921 Words | 4 PagesSecondary endpoints included the number of vomiting episodes during oral rehydration and the rates of intravenous hydration among each group. It was found that the proportion of pediatric patients who received ondansetron and subsequently vomited during oral rehydration therapy was lower than those patients who received placebo (14% vs. 35%; RR = 0.40, 95% CI 0.26 to 0.61, P < 0.001), the mean number of vomiting episodes (0.18 vs. 0.65; RR = 0.30, 95% CI 0.18 to 0.50, P < 0.001) and rates of intravenous hydration (14% vs. 31%; RR = 0.46, 95% CI 0.26 to 0.79, P = 0.003) were lower in the ondansetron group than in the placebo group, and the amount of oral rehydration fluid consumed was higher in the ondansetron group than in the placebo group (239 mL vs. 196 mL, P < 0.001). Though the study reported no serious adverse events, it was shown that those patients receiving ondansetron had more diarrhea episodes during oral rehydration compared to placebo (1.4 vs. 0.5, P < 0.001). Thus, this trial showed that ondansetron was more effective than placebo in reducing
Case Study: Deca Durabolin
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Exubera Research Paper
1678 Words | 7 PagesThis makes Lantus Germany's largest and most important export in terms of pharmaceutical products. [23] The central advantage associated with insulin glargine is the convenience of the once-daily injection and the absence of suspension problems, leading to the achievement of glycaemic control for the diabetic individual. [26] The disadvantage associated with it is that unfortunately, it cannot be mixed with soluble insulins as to do so results in precipitation. This means that patients requiring a mixture of insulins must increase their daily injections to achieve glycaemic control.
Benefits Of The Banting Diet
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Disadvantages Of Phototherapy
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