Primary infection occurs in epithelial cells leading to a skin rash and fever as a phenotype. When virions spread to adjacent sensory neurons, a lifelong infection is established (Owen, Crump, & Graham, 2015). Both primary and secondary diseases have a significant morbidity and mortality but thanks to advances in diagnostic and the production of vaccines, it is possible to decrease their burden (Gershon, 2013). 1.1 Varicella: Varicella (chickenpox), the primary infection of VZV, is characterized by cutaneous eruption typically seen in children. In adults, this primary infection is more severe and in immunocompromised patients, it can be followed by complications such as, high fever, pneumonia, encephalitis and hepatitis (Gershon et al., 2013).
The infection has an “incubation period of four to six weeks, in children this may be shorter,” (Mayo). The illness is spread most often by close contact and kissing. Common symptoms include general feeling of being ill, fatigue, sore throat, fever, decreased appetite and headache. As the illness progresses the tonsils swell and develop a whitish-yellow covering and the lymph nodes become more swollen and painful. One of the complications of mononucleosis is a ruptured spleen.
However, it is likely due to an abnormal response of the immune system. Food or bacteria in the intestines, or even the lining of the bowel may cause the uncontrolled inflammation associated with Crohn 's disease. Signs and Symptoms: The symptoms of Crohn 's disease depend on where the disease occurs in the bowel and its severity. These are some symptom examples Chronic diarrhea, often bloody and containing mucus or pus Weight loss Fever Abdominal pain and tenderness Feeling of a mass or fullness in the abdomen Rectal bleeding
Pneumonia is a frequent cause of hospitalization and illness amongst children, with incidence of 4% per year under the age of 5, 2% per year in children 5-9 years of age and 1% per year in older children and adolescents.  Out of these a small number of patients develop persistent and recurrent pneumonia, which presents a big challenge for physicians to manage and diagnose. A proper approach to face this challenge first requires a proper definition of the term recurrent pneumonia. Pneumonia is as an acute illness characterized by cough, fever and tachypnoea in a generally unwell child, with labored breathing or abnormalities (bronchial or diminished breath sounds or crackles) on chest auscultation.  Recurrent pneumonia is defined as two or more episodes of pneumonia in a year, or three or more ever, with radiographic clearing between occurrences, and is reported in 7–9% of children with pneumonia.
A healthy individual usually becomes ill after touching their eyes, nose, or mouth after coming in contact with an contaminated object. Symptoms of the common cold includes: sneezing running nose cough congestion headache sore throat loss of appetite mild fever Although the common cold can typically last 7-14 days, there some complications to aware.
As early as childhood he showed signs and symptoms of Parkinson’s disease which was later revealed as encephalitis lethargica. Acoording to the CNS forum (2000-2015) “Patients experienced a reduced level of awareness, possibly caused by swine influenza or some type of herpes-like virus. When they awoke, about half would have severe Parkinson's-like symptoms including rigidity, bradykinesia, slight tremors, and curious eye movements, so-called occulogyric crises - an uncommon symptom in idiopathic Parkinson's disease.” Dr. Sayer, who was played by Robin Williams, was applying for a job at the hospital where Leonard was confined, although Dr. Sayer he was not able to work with human patients before he was hired because the hospital was currently understaffed. Sayer, despite the skepticism of his colleagues, was determined to uncover what really happened with the patients and be able to help them regain normality. He then met Leonard, who became the subject on testing the drug L Dopa.
Even then, the metastasis rate is quite low, with the exception of SCC of the lip, ear, and in people who are immunosuppressed. Melanomas are the least frequent of the 3 common skin cancers. They frequently metastasize, and could potentially cause death once they spread. Less common skin cancers include: dermatofibrosarcoma protuberans, Merkel cell carcinoma, Kaposi 's sarcoma, keratoacanthoma, spindle cell tumors, sebaceous carcinomas, microcystic adnexal carcinoma, Paget 's disease of the breast, atypical fibroxanthoma, leiomyosarcoma, and
It can be caused by a number of factors such as : Gastroenteritis - this is typically acquired from food or water that has been contaminated by faeces or directly from another infected person. This causes infectious diarrhoea and the infectious agents can be bacteria, viruses or parasites. Common causative bacterial agents are Escherichia coli, Vibrio cholerae, Shigella dysenteriae and Clostridium difficile. Food allergies or food intolerance such as lactose intolerance. An adverse reaction to medication such as penicillin, antacids and laxatives.
Summary Ischemic colitis is damage to the large intestine due to reduced blood flow (ischemia) to the colon. Some of the symptoms of this condition include abdominal pain or tenderness, bloody stools, and an urgent need to have a bowel movement. Diagnosis usually includes a procedure to examine the inside of the colon using a scope passed through the rectum
Lichen planus (LP) can occur on the skin alone; h. However, it is also seen inside the oral cavity, on the scalp, nails and the genital mucosa. Symptoms of lichen planus may wax and wane. They may increase during periods of trauma, or during stress and anxiety. Cutaneous LP Lichen planus is a papulosquamous skin disease which produces intense itching (pruritus). It consists of lesions which are characterized by six P’s: • Pruritic • Purplish • Planar • Polygonal • Papules • Plaques The rash starts suddenly, and occurs on the inside of the wrists, the legs and the trunk.
For newborns, symptoms include: lethargy, seizures, irritability and poor feeding. Both meningitis and encephalitis are contagious and can be spread through contact of saliva, mucus and feces. The disease can also be spread y kissing, sharing drinks, toothbrushes, lipsticks and
Clostridium Difficile Infection Clostridium difficile (C. difficile or C. diff) infection is a condition that causes inflammation of the large intestine (colon). This condition can result in damage to the lining of your colon and may lead to colitis. This condition can be passed from person to person (contagious). CAUSES C. diff is a bacterium normally found in the colon. This condition is caused when the balance of C. diff is changed and there is an overgrowth of C. diff.