MYELOMA Myeloma is a blood cancer that affects the plasma cells in the blood. The blood production helps stop the developing of the myeloma. The spine and the hips are the first bones attacked. The body will not make any new plasma cells to fight the disease. The bone barrow is the first body system to be damaged and unable to make more cells. The bone marrow will show the damage as a nonmalignant osteoporosis. The lesions on the bone marrow could be painful or break a bone. It is not for sure that genetics is the reason for myeloma. The blood platelets help the body fight the myeloma. Myeloma is called multiple myeloma when the plasma clumps and at many sites. When one site is detectable it is called solitary …show more content…
The measuring levels of the immunoglobulins is one way of tracking the extent and progression of the disease. If the immunoglobin that is secreted from myeloma the normal immunogobulin will be suppressed. Liquid and solid bone marrow samples are examined under a microscope to test for myeloma. The smoldering multiple myeloma is a condition that involves the findings of abnormal plasma cells that produce a monoclonal protein, but no symptoms. Indolent multiple myeloma this type of myeloma have an elevated number of abnormal plasma cells in the bone marrow that may or may not produce monoclonal protein. They also have mild anemia or bone lesions, but they have no symptoms. Symptomatic multiple myeloma is the full active …show more content…
The symptoms of myeloma are mostly pain but the ribs and spine are the most effected areas in the body causing chest wall or back pain. If the myeloma is advanced can cause bone degeneration which can press on the nerves causing little feeling, burning sensation and paralysis. It can cause high levels of calcium destroying the bones at a fast rate. The other complications cryoglobulinemia this rare condition produce a protein that precipitates, when it is exposed to cold temperatures. Amyloidosis occurs mostly in people whose myeloma has the light chain components of immunoglobulins to form a sticky protein called amyloid, impairs the function of whichever organ it is in. The kidney damage due to myeloma is fatigue, nausea, vomiting there also could be no signs and could cause foamy urine. Hyperviscostly syndrome can cause bruising from the mouth, nose, headaches, confusion, sleepiness, and problems with feeling their limbs. A bone marrow sample is taken to see what stage you can be treated
When the sarcolemma is disrupted, a release of intracellular muscle components such as creatinine kinase, muscle enzymes, and myoglobin occurs. Direct trauma combined with various other risk factors including alcoholism, muscle exertion, infections, hyperthermia, diabetes, status asthmaticus, fasting, and certain drugs can result in the development of rhabdomyolysis. The symptoms of rhabdomyolysis are often subtle and can include muscle pain (especially in the lower back or calves), fever, fatigue, vomiting, nausea, confusion, anuria, and generalized weakness. Dark reddish brown urine is also often noted in people with this condition as a result of
T cells are produced to attack the antigens of tumors and B cells are produced to make antibodies that are specific to the antigens of a tumor. An older individual’s immune system could react at a slower
Also, a brown or tea colored urine can indicate that there is a larger amount of toxins in the blood such as myoglobin and CK which leads to rhabdomyolysis. When seeing by a physician, they may also ask if you have had a decreased amount of urine produced as well as muscle weakness and stiffness. These all are signs that point to rhabdomyolysis of the skeletal muscle. Tests that can be done to see if it is in fact rhabdomyolysis extend from testing the amount of CK in the blood as well as the levels of serum calcium and even urine myoglobin tests. A Urinalysis can also be used to see if you are effected by the disease.
When I see somebody with cancer, I get really mad, I say to myself, ”Why must this disease be real. Why did God create something so horrible that it can affect anybody.” If it was I who had ten million dollars, I would donate it to St.Jude's Cancer Research Facilities because it is a deadly disease, it is a real-nonprofit research organization, and it covers all expenses for families. Cancer is among the top ten leading causes of death in the world. This disease takes nearly eight million lives every year.
Task 2 Degenerative Diseases - Alzheimer’s - There are seven risk factors of Alzheimer’s disease and they include: - Age: After 65 the risk will increase, symptoms can start developing as early as their 30s for people with rare genetic changes. - Family history and genetics: If one of your parents has Alzheimer’s, you will become more at risk of developing it also and this can also be from your sibling also. - Sex: Even though women live longer than men, they may be more at risk of developing this disease than men. - Mild cognitive impairment: People with MCI are more at risk but it is not certain that they can develop dementia later in their life.
We’ve always been taught that the sun is our friend. It warms us, helps grow our food, gives us light, all good things. Unfortunately, the sun has become less of a friend over the past few decades. As the sun’s UV Rays become more and more of a concern, so has the incidence of skin cancer, malignant melanoma.
It is also felt within the vagina or rectum during the menstrual cycle. In many cases the person’s organs will no longer appear smooth and pink but have bloody lesions, black speckles and blood clots around the
Bone cancer isn’t a very common cancer. It accounts for much less than one percent of all cancers. Around 2,300 cases of bone cancer are diagnosed each year. Bone cancer is a serious disease that has multiple different types and treatments.
Psychosocial Advances in Oncology Research and Practice In the 1800’s, a cancer diagnosis was viewed as the equivalent of death (Holland, 2002). In this day and age, there was no known cause or cure, and it was considered inhumane to reveal the diagnosis to the patient. In a constantly changing and advancing society, this ideology was transformed as the result of an accumulation of technological advances, education, and research initiative. This led to the acceptance of the notion of cancer worldwide.
The cancer of the blood(leukemia ) do not form solid tumor. CLASSIFICATION OF TUMORS The types of solid tumors are – Sarcomas and Carcinomas. The tumors that are formed in bone , lymph vessel , muscle and tendons are called sarcomas.
This serious compression of nerves, blood vessels, and muscles can cause tissue damage and problems with blood flow. This is due to direct or indirect serious muscle injury, such as a building collapse. This can lead to kidney failure. While someone with extreme trauma has a high chance of developing crush syndrome, there are people who have a genetic predisposition to develop rhabdo. Early treatment of rhabdomyolysis can result in complete recovery.
One of the troubling things about it is that sometimes the signs or symptoms will not arise until the cancer has made a significant amount of progression. Some cancers may cause extreme tiredness or fatigue. This is because the multiplication of cancer cells takes up a lot of the body’s energy. Cancer cells can also release substances into your body that affect nerves and muscles and causes symptoms that can make a person weak or dizzy. For example, some pancreatic cancers release substances that cause blood clots in the veins of the legs.
The aforementioned ring forms that are seen within red blood cells can vary significantly and can be easily misinterpreted as Plasmodium falciparum (i.e. a malaria parasite), although the absence of the hemozoin pigment should point to Babesia parasites. And indeed, there are cases described in the literature when the patient was erroneously diagnosed with malaria, which may result in misguided treatment and pose a serious risk to the
Symptoms can be most times severe and sudden but it isn’t uncommon for someone not to notice for a couple days. Pain can usually be noticed in the abdominal area and in the lumbar region of the back. Other symptoms may include feeling sick, throwing up, an above normal fever, and a pulse rate higher than
Your risk of developing this disease increases as you age. Other risk factors involved are genetic factors, smoking, and chronic abuse of pain medicines. Early stages of kidney cancer may have no symptoms, but during later stages, these may manifest as a lump in the abdomen, blood in the urine, unexplained weight loss, chronic pain in the side, loss of appetite. Treatments include surgery, radiation, chemotherapy, biologic therapy and targeted therapy. 4.