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Neuropathic Pain Analysis

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2.3 Definition of neuropathic pain
Neuropathic pain was assessed using the painDETECT questionnaire (26). This validated one-page questionnaire is specifically directed to neuropathic pain symptoms and is easily to be completed during a clinic visit. The painDETECT questionnaire comprises a total of 12 questions about the severity, course and quality of pain. Pain intensity is to be rated on a 0-10 numerical rating scale (NRS) for three pain characteristics: current pain, strongest pain during the past four weeks, and average pain during the past four weeks. Common pain sites are then to be marked on a body diagram and the participant is asked if pain radiates to other body regions (yes/no). Next, the participant is asked to choose one of four different pictures that best describes …show more content…

All parameters were measured immediately. Blood glucose was analyzed using a hexokinase method (GLU Flex, Dade Behring). Total serum cholesterol analyses were carried out using a CHOD-PAP method (Dade Behring). Serum creatinine was determined using a modified kinetic Jaffé reaction (19). HbA1c was measured with a reverse-phase cation-exchange high pressure liquid chromatography (HPLC) method (Menarini, analyzer HA 8160).

2.7 Statistical …show more content…

A recent study based on data from the General Practice Research Database (GPRD) in the UK including 5,920 patients with post-herpetic neuralgia (PHN), 5,340 with painful diabetic neuropathy (PDN), and 185 with phantom limb pain (PLP) found that an antidepressant or an antiepileptic was prescribed as part of a first-line treatment for 57.0% of PHN patients, 70.5% of the PDN cohort and 61.1% of the PLP cohort; amitriptyline and gabapentin were the

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