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Obstructive Sleep Apnea

272 Words2 Pages

Study Objectives: To evaluate the impact of obstructive sleep apnea (OSA) on neurocognitive function and brain morphology in elderly patients with depression and cognitive impairment. (DEP-CI). Design: Prospectively screened OSA in patients from the Donepezil Treatment of Cognitive Impairment and Depression (DOTCODE) trial. OSA was defined as a Stop-Bang scale score of ≥5 (the specificity is 79.7% for OSA diagnosis). MRI was used to evaluate cerebral microvascular burden and hippocampal volume. Setting: Memory Disorders and Late-life Depression Clinics. Participants: Last 25 patients from DOTCODE trial were studied; 10 were in the OSA group, 15 were in the non-OSA group, and 19 had MRI. Interventions: Sixteen-week of the initial antidepressant

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