Parkinson Disease Case Study
Anaesthetic Management of a patient with Parkinsonism Posted for Wide Excision of Skin Adenexal Tumour in the Axilla: A Case Report Introduction
Parkinsons disease has been known since biblical times but it was first formally described by James Parkinson in the 18th century and termed “the shaking palsy”. Although the aetiology of the disease is unknown, age has been identified as the most consistent risk factor. Parkinsons disease affects approximately 3% of the population over 66 years of age and with increasing age of the general surgical patients it is becoming an important cause of perioperative morbidity
Parkinsonism is due to the imbalance of the mutually antagonistic dopaminergic and cholinergic systems of the basal ganglia. Pigmented
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Volatile anesthetics can alter the dopaminergic balance in the brain, but whether they exacerbate PD is unknown. Propofol produces both dyskinesias and ablation of resting tremor, suggesting that it has both excitatory and inhibitory effects in this patient population. But both volatile agents as well as propofol has been successfully to sedate patients with PD during deep brain stimulation surgery. Dexmeditomidine appears to be safe and when used in deep brain stimulation surgery has advantage of not interfering with motor symptoms. Ketamine should be used with caution because of potential interaction between levodopa and ketamine’s sympathomimetic activity. Butryophenones( eg:-droperidol) and phenothiazines , which block dopamine receptors and exacerbate PD should be avoided. Ondansettron appears safe in preventing and treatment of emesis in patients with PD and is also used in treatment of psychosis induced by long term levodopa therapy. Opioids are more succeptible to produce muscle rigidity in patients with PD. Meperidine should be avoided in a patient taking monoamine oxidase inhibitor becaouse of the potential to produce stupor, rigidity, agitation and hyperthermia. Responses to depolarizing and nondepolarizing muscle relaxants are thought to be normal in PD, despite a single case report of succinylcholine induced
Muscle Spam Case Study
533 Words | 3 PagesThey are not recommended for long-term use because long-term efficacy is unproven and there is a risk of dependence. Most guidelines limit use to 4 weeks. Additionally, ODG states that benzodiazepines are not recommended as muscle relaxants, due to rapid development of tolerance and dependence. There appears to be little benefit for the use of this class of drugs over nonbenzodiazepines for the treatment of spasm. The patient has chronic low back pain.
Nuplazid Case Interview
1510 Words | 7 PagesNervous and embarrassed, Gina kept her hallucinations a secret from her family for a month before deciding to open up about her health and making an appointment with the doctor. The diagnosis of Parkinson’s was a “complete shock” to Gina and her family, but together they employ a “mind over matter mentality” to help them cope. About one year ago, Gina started on Nuplazid to treat the hallucinations. On Nuplazid, they’ve experienced: (QOL) Gina’s quality of life has significantly improved since starting Nuplazid.
Rapid Consequence Intubation (RSI)
644 Words | 3 PagesEtomidate is a short acting sedative that avoids affecting respiratory, cardiac and circulation centers, meaning less adverse reaction in the patient (Mason et al., 2013). Midazolam is a benzodiazepine sedative that can be used in RSI, but tends to cause hypotension in patients (Mason et al., 2013). Ketamine is another sedative that can be used, but it is usually a third choice after etomidate or midazolam because of its adverse affects (Mason et al., 2013). Propofol is the final sedative or hypnotic that is used in RSI, it has adverse effects including hypotension, and because of its short acting period is used primarily in conscious sedation procedures and not RSI (Mason et al.,
Bowel Case Studies
1465 Words | 6 PagesDOI: 3/24/2010. The patient is a 55-year-old male machine shop lead who sustained back, neck, right shoulder and internal injuries due to repetitive work. As per medical report dated 04/27/16, the patient has a history of a spinal cord injury secondary to cervical stenosis. He underwent emergent decompressive cervical laminectomy on 3/26/10. The patient has ongoing neurogenic bowel, ongoing neurogenic bladder, severe depression and pain.
Parkinson's Disease Essay
639 Words | 3 PagesParkinson’s disease is a “disorder of the nervous system that affects movement” (Staff, 2015), but does not have an acute onset. Usually symptoms start with a slight tremor in the hands and then slowly progresses to other parts of the body (Staff, 2015). Even though most people have fast, shaking, movements, Parkinson’s can also cause stiffness or slow movements. According to Mayo Clinic Staff, early signs of Parkinson’s disease may include diminished facial expressions, absence of swaying arms when walking, and “speech may become soft or slurred” (2015). Unfortunately, Parkinson’s does not have a cure, but there are medications out there to help symptoms as well as brain surgeries.
Awakenings Research Paper
719 Words | 3 PagesWith this drug what was seen was a very, very significant improvement in both motor and cognitive skills at the same time,” Moussa told Healthline. Parkinson’s specialists who weren’t involved in the study cautioned that other drugs have looked promising early on only to show no benefits in larger clinical trials. But they agreed the drug seems to accomplish something that no previous candidates have. “If it really works it could be an amazing big deal,” said Dr. Caroline Tanner, Ph.D., the director of Parkinson's Disease Research, Education and Clinical Center at the San Francisco Veteran's Affairs Medical Center. Dr. Michael Okun, the national medical director of the National Parkinson Foundation and a professor at the University of Florida College of Medicine, said that if the drug holds up in bigger trials, it could be prescribed for patients quickly because it’s already FDA approved.
Michael J. Fox: Parkinson's Disease
854 Words | 4 PagesIn conclusion, Parkinson’s is very hard to cope and live with. Day-to-day life is affected by it to the point where it is frustrating to both the patient and caregiver. This is what life is like for Michael J. Fox and the millions of people across the globe who struggle daily with
The Awakenings Movie Review
1479 Words | 6 PagesThe movie “Awakenings” is a story about a doctor's extraordinary work in the Sixties with a group of catatonic patients he finds languishing in a Bronx hospital. Speculating that their rigidity may be akin to an extreme form of Parkinsonism, he seeks permission from his skeptical superiors to treat them with L-dopa, a drug that was used to treat Parkinson's disease at the time. It was Dr. Sacks' inspired understanding of this state as possibly responsive to the drug L-dopa that led to the opening of
Parkinson's Research Paper
577 Words | 3 PagesAwakenings, audiences get an inside view of the goings on at a hospital with catatonic patients. In this paper I will be discussing the conditions of the hospital and the relationships between the people who worked there and the residents of the hospital. Their attitude toward Dr, Sayer, and the staff's attitude toward each other. I will also be discussing the symptoms and treatment of the patient's disease of Parkinson's . Although the conditions in the hospital were sanitary and well kept, it was much more of a prison with its countless barred windows and locked doors.
What Is Patient Treatment In The Awakenings
504 Words | 3 PagesThe patient's Dr. Sayer was treating did not have Parkinson’s disease but had symptoms of it. It was wrong to give these patients this drug because they did not have the disease the drug was for. In the end of the movie Leonard started having side effects from the drug. In experimental material this was good because the doctors found the drug did not work. It was also wrong, it gave Leonard false hope that he would be better when he wasn’t.
Predict Seizures In Dogs
835 Words | 4 PagesParkinson’s Disease Freezing Parkinson’s Disease patients suffer from more than just stiffness and tremors. They also deal with freezing. This is when their feet freeze, even though the rest of their body is still moving. Because this results in falls, many Parkinson’s Disease patients become afraid to
Parkinson Disease Affecting Dale Maxin's Life
402 Words | 2 PagesThe disease that Dale Maxin has is known as Parkinson Disease. This disease has affected Dale 's life in a very negative way. It has caused him much grief. Medication helped him to cope with Parkinson for a period of time, however; even the medication has reached a point where it n longer helps. His wife is who he has to depend on with help for everyday things.
Parkinson Disease Research Paper
2136 Words | 9 PagesDiscuss the common clinical manifestations of PD. There are about twelve or so common symptoms or manifestations that you need to discuss in regards to what they are and what causes them to appear. There are also some manifestations that are not as common and I would like you to discuss those as well. (4 points) Tremor- this beings in a limb.
Awakenings Movie Review Essay
1136 Words | 5 PagesThe film “Awakenings” was a hit film in 1990 and an award winning drama movie. The movie depicts a particular disease that was the Post encephalitis Parkinson’s disease and the drug that was L-Dopa medication that used to treat it very accurately and effectively. “Awakenings” was all about the victims of epidemic of encephalitis lethargica or Post encephalitis Parkinson’s disease. But a new doctor, Dr. Sayer discovered the L-Dopa medication to try to treat some patients that appear to be catatonic and offers the prospect to reviving them. Speculating that their rigidity may be analogous to a severe form of Parkinsonism, he seeks permission from his sceptical superiors to treat patients
Eponym And Parkinson's Disease
144 Words | 1 PagesAn eponym as a medical term is defined as drug or disease which is named after a person. This could be either the person who discovered the drug or disease or the person who first had a disease. For example, Parkinson 's disease is named after an English physician who first described it in a monograph in 1817. The disease is a progressive neurological disease that typical starts to develop around the age of sixty. It is caused by the break down and death of neurons inside the brain, the reason for this is currently still unknown.
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