Chronic Periodontitis

Introduction: Chronic periodontitis (CP), the commonest type of periodontal disease, it is an infectious disease resulting in inflammation within of the tissues supporting the teeth, progressive loss of attachment and bone loss. It is closely related to several systemic diseases, such as diabetes and cardiovascular disease. The link between periodontal disease and chronic kidney disease (CKD) may be due to infection and inflammation. The periodontal inflammatory state may increases the chronic inflammation present in CKD, thus decreasing renal function. Periodontal therapy may reduce inflammation and improves endothelial function.

Aim:- To investigate the effect of mechanical non-surgical periodontal therapy on serum renal function

Prior approval for the study was obtained from the local ethical committee. Patients with chronic generalized periodontitis [(moderate and severe) according to CDC working group, 2007 criteria]. Age ranging from 35-60 ( mean 45) years, should have at least 20 natural teeth, who have not received periodontal therapy, within preceding six months were included in this study. Tobacco in any form and alcoholics, any other systemic disease which can alter the course of periodontal disease, subjects should have pregnant, women on hormone replacement therapy or hormonal contraceptives, patients taking steroidal or non-steroidal anti-inflammatory drugs (previous 3 months) or antibiotics (previous 6 months), anti-inflammatory drugs and antibiotics in the previous six month and patients with aggressive periodontitis were excluded from this

(p=< 0.00001). But on evaluation of the Probing depth at baseline there was significant difference in CG & TG (p=< 0.00001), after 1 month also there was significant difference between CG & TG. (p= 0.0017).Significant difference is also seen in case of CAL evaluation at baseline (p=< 0.00001) & after 1 month (p=0.00013) Comparison of serum examination it shows that, there was no significant difference in serum Urea level at the baseline (p=0.274) & after intervention & 1 month evaluation it show significant difference difference between CG & TG. (p=0.000145), but on evaluation of serum creatinine level there was significant difference between CG & TG at baseline (p=0.00025) but no significant difference after 1 month. (p=0.79).Serum bilurubin shows statistical significant difference both at baseline (p=0.036) & 1 month (p=0.000113) After Intragroup evaluation of all periodontal parameters & serum parameters of CG at baseline and at 1 month shows that there is no statistical significant difference [Table No. 3] but TG shows statistical significant difference between at baseline & 1months in periodontal & serum parameters. [Table no.