A., Fisman, D. N., Moineddin, R., & Daneman, N. (2014). The magnitude and duration of Clostridium difficile infection risk associated with antibiotic therapy: A hospital cohort study. PLoS One, 9(8), e105454. doi:http://dx.doi.org.southuniversity.libproxy.edmc.edu/10.1371/journal.pone.0105 Connelly, L. M. (2014). Use of theoretical frameworks in research.
Lorazepam can also be used as premedication for anxiolysis at a dose of 2 mg as bolus and its elimination half life is 13.8 hrs. Though Lorazepam onset of action is delayed, it produces a constant sedative effect on the CNS when bolus dose precedes a continuous infusion. This property of lorazepam made available in the critical care medicine.5 Aim To compare the safety and efficacy of Lorazepam over a well-established premedication, Alprazolam, in producing sedation and anxiolysis effects. Objectives 1. To determine and compare the sedative and anxiolytic effects of orally administered Alprazolam and Lorazepam in control and treatment group at time intervals of 30, 60 and 90 minutes.
TITLE: PERIPHERAL INTRAVENOUS CATHETER SITE INFECTION PRESENTING AS ENDOCARDITIS- A PREVENTABLE COMPLICATION Abstract: Nosocomial infections pose a global safety concern for hospitalized individuals as well as health care providers. About 10 to 30% of patients acquire nosocomial infection according to Hospital Infection Society, India. Common hospital-acquired infections are respiratory, urinary tract, surgical wound infections and infections associated with intravascular catheters. We discuss here a case of a 35-year-old woman who had an intravenous cannula inserted at her right wrist at the time of her laparoscopic cholecystectomy. She developed fever along with redness and tenderness at the catheter insertion site on 4th postoperative day.
Thermo reversible gels mostly prepared from poloxamers are predominantly used.  The suitability of poloxamer gel alone or with the addition of hydroxyl propyl methyl cellulose (HPMC), sodium carboxy methyl cellulose (CMC) or dextran was considered for epidural administration of drugs in vitro.  The compact gel depot acted as the rate limiting step and significantly extended the dural permeation of drugs in comparison with control solutions. J. M. Barichello et al. evaluated Pluronic F127 gels, which contained either insulin or insulin-PLGA nanoparticles with conclusion, that these formulations could be used as a controlled delivery system.
MedClin North Am 1985, 69:849. Serter R, Demirbas B, Culha C, Cakal E: The effect of L-thyroxinereplacement therapy on lipid based cardiovascular risk insub clinical hypothyroidism. Invest J Endocrinol2004, 27:897-903 .Waring AC, Rodondi N, Harrison S, Kanaya AM, SimonsickEM,Miljkovic I, Satterfield S, Newman AB & Bauer DC. Thyroidfunction and prevalent and incident metabolic syndrome in olderadults: the Health, Ageing and Body Composition Study. ClinicalEndocrinology 2012 76 911–918.
Introduction: Quetiapine Fumarate (QF) is a psychotropic agent indicated for the treatment of schizophrenia and manic episodes associated with bipolar disorder. QF possesses good solubility in aqueous fluids (1) and ethanol. Quetiapine is available in the market with the brand name of Seroquel XL (2). Inadvertent, rapid drug release in a small period of time of the entire amount or a significant fraction of the drug contained in a prolonged release dosage form is often referred to as “dose dumping”. Jhonson F. et al.
One of the principal treatments approved by the Food and Drug Administration (FDA) for Alzheimer’s disease is a drug named Rivastigmine (Exelon®). The beginning of this essay starts with how the neurons relay messages in the central nervous system followed by the pathophysiology of Alzheimer’s disease then illustrates the function of Rivastigmine to reduce the effect of Alzheimer’s disease. PATHOPHYSIOLOGY Neurons communicate with each other by relaying electrical and chemical signals across the synapses (Stufflebeam, 2008). Synapses are places usually formed between the axon terminals and dendritic spines. The presynaptic neuron is the neuron that transmits the signal whereas the postsynaptic neuron receives the signal.
Retrieved from acandiana addiction center: http://www.acadianaaddiction.com/prescription-drugs/oxycontin Benefits Of Oxycodone. (n.d.). Retrieved from Benefits Of everything that matters: http://benefitof.net/benefits-of-oxycodone/ OxyContin: Pain Relief vs. Abuse. (n.d.).
Pharmaco-therapeutic group: Remedy for inhalation for general anesthesia. Code: АТХ: N01АВ01 Pharmacological properties Pharmacodynamics: Halothane is a drug for inhalation anesthesia from the group of fluorinated aliphatic compounds. Causes the rapid introduction in anesthesia without \or with a minimal
COMPARISON OF INTRAVENOUS DEXMEDETOMIDINE VERSUS ESMOLOL FOR ATTENUATION OF HEMODYNAMIC RESPONSE TO LARYNGOSCOPY AND ENDOTRACHEAL INTUBATION Abstract: Background: Esmolol has an established role in attenuation of hemodynamic response to laryngoscopy and endotracheal intubation. We studied the effect of Dexmedetomidine compared to that of esmolol in this study. Aim: To study the role of dexmedetomine in attenuation of hemodynamic response to laryngoscopy and oral endotracheal intubation compared to that of esmolol hydrochoride in patients posted for elective surgery under general anesthesia. Study Design: Prospective randomized study-double dummy blinding method Material and Methods: 60 ASA I patients, aged 18-60 years randomly divided into two groups; Group A patients received dexmedetomidine 1mcg/kg diluted in 50ml
Nursing consideration: Require regular monitoring of activated partial thromboplasitn time (aPTT) and needed frequent heparin dose changes (Brunner and Suddarth’s, et al, 2010: 765). Fibrinolytic therapy: This therapy is given to dissolve the thrombus in the artery and restore the blood flow. There are two fibrinolytic drugs which are streptokinase and Recombinant tissue plasminogen activators (r-TPA) which includes Alteplase, reteplase and tenecteplase (Brunner and Suddarth’s, et al, 2010: 772). Fibrinolytic therapy would be commenced within 4-6 hours of myocardial infarction to restore blood flow, reduce oxygen demand and reduce myocardial tissue damage (Silvestri,