Postoperative Pain Case Review

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Efficacy And Safety Of Post-Cesarean Section Incisional Infiltration With Lidocaine Alone Versus Lidocaine And Epinephrine In Reducing Postoperative Pain: A Randomized Controlled double-blinded Clinical Trial
Ahmed A. Tharwat (MD)*, Amr H. Yehia (MD, MRCOG)*, Karim A. Wahba(MD, MRCOG)*, Abd-ElRahman G. Ali (MSc.)**
* Department of Obstetrics and Gynecology
Ain Shams University Maternity Hospital
** Department of Obstetrics and Gynecology Misr Al-Gededa Military Hospital

Correspondence : Dr Karim A. Wahba, Consultant of Obstetrics & Gynecology, Ain Shams University Maternity hospital, Abassia Square, Cairo, Egypt.
Email: Karimwahbaobgyn@yahoo.com
Tel.: 00201001436033
ABSTRACT
Background: Sufficient control of post-cesarean section pain is imperative to relieve patients’ discomfort, as well as to enhance breast-feeding performance , infant care and enhance patient recovery as a whole.
Objective: is to assess the efficacy and safety of post-cesarean section infiltration with lidocaine and epinephrine versus lidocaine only to reduce post-incisional pain and hence enhance patient recovery.
Patients and Methods: it was a prospective randomized controlled double-blinded clinical trial
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Thus, it was estimated that a sample size of 64 patients per group would achieve a power of 80% (type II error, 0.2) to detect a medium effect size (Cohen’s d = 0.5) as regarding the outcome measures. The effect size (d) was calculated as follows: d = (m1 – m2)/s, where m1= mean of the control group, m2 = mean of the experimental group and s = pooled standard deviation. A number of 70 patients were included in each group (estimating 10% drop

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