Preeclampsia Case Study

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Investigation of Preeclampsia
And Hellp syndrome

Student name: Amer Binessa.
Student number: D13123451
Subject: Biochemistry
Lecturer: Dr Frank Clake
Date:01/11/2016

Clinical information
A 35 years old female presented at the national maternity hospital (NMH) at week 12 gestation for liver function test (LFTs). According to the NMH reference ranges the patient had normal LFTs (1). The expected date of the delivery was 15/10/2016. In the week 37+2 gestation the woman felt pain and called the community midwife office they took her immediately to the delivery ward in NMH and they found that she has a high blood pressure 142/90, high urate and proteinuria which indicate preeclampsia disease. Preeclampsia is a condition where the pregnant woman has high blood pressure and proteinuria (2). The patient case becomes worse because she developed HELLP syndrome after the delivery of the baby. In order to confirm the preeclampsia multiple tests were carried out.

Patient History
No previous history

Results: Table1: This table shows the results of patient tests
Date and Time Test Result Reference Range
19/04/2016
12:08

Week12 gestation Albumin
AST
ALT
Alkaline phosphatase
Bilirubin Total 36 g/l
21 IU/I
10 IU/I
…show more content…
bilirubin test is used to test bilirubin in the liver. Bilirubin is divided into direct(conjugated) and indirect bilirubin(unconjugated). Direct bilirubin is produced by the liver when the sugars bind to the bilirubin then it goes to the bile and conjugated and then to the small intestine and excreted by the stool. Indirect bilirubin is where the heme is liberated from the breakdown of hemoglobin which then is unconjugated and it goes to the liver by the protein and some of it can be seen in the blood. Total bilirubin = conjugated + unconjugated. Bilirubin yellow is changed to biliverdin green by the oxidation of ferrycianide at 480/600 nm

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