Proton Pump Inhibitor Analysis

This is because of the stomach acid released by the digestive system. This powerful acid reduces food, but sadly, it does not exactly differentiate between "food" and "teeth." As a result, tooth enamel erodes. Tooth enamel is the film that protects the teeth from the typical decay that happens everyday. Frequent vomiting also discolors teeth and disfigures them.

The mucus can also block your pancreas (an organ in your stomach) which will disable you to not digest your food properly. Usually, the mucus in the lungs traps germs which will eventually be cleaned out of the lungs. It will also affect a person’s lungs and digestive system which will lead to constant lung infections. Cystic fibrosis doesn't only affect your breathing, but it also affects your weight, your bones and can cause Type 1 diabetes. Many people who have cystic

Diuretics cause the kidneys to remove salt and water from the blood. The extra fluid is removed through urination. This loss of extra fluid lowers the volume of blood the heart pumps. • Beta blockers. These prevent the heart from beating too fast and improve heart muscle strength.

Alka Seltzer mixture mainly consists of 3 active ingredients; aspirin, citric acid and sodium bicarbonate. The functions of the following components are as follows; Aspirin acts a pain reliever and as an anti-inflammatory (which reduces swelling and inflammation). It does this by preventing the action of a substance known as cyclo-oxygenase which produces chemicals in the body. Sodium hydrogen carbonate and citric acid neutralizes and reduces stomach acid when they react with water. The excess bicarbonate however, is responsible for the buffering action of the mixture.

ABSTRACT: Pantoprazole sodium is an antiulcer drug. This compound inhibits gastric acid formation and thereby it is very efficient for the treatment of gastric and duodenum ulcers. But pantoprazole sodium is acid labile drug that will degrade in acidic environment of stomach resulting in therapeutic inefficacy. Hence it is necessary to bypass the acidic pH of the stomach which can be achieved by formulating delayed release dosage forms (single unit or multiple units) by using different enteric polymers The present study was an attempt to formulate and evaluate enteric coated tablets for pantoprazole sodium sesquihydrate. Different core tablets were prepared using different superdisintegrants (Sodium starch glycolate, croscarmellose sodium,

Chapter One: Introduction Proton pump inhibitors were initially introduced in 1980 and are widely used for the management of gastric acid conditions such as gastric ulcers, duodenal, reflux oesophagitis, and gastroesophageal reflux disease. Proton pump inhibitors decrease the acid production by enzyme blocking within the stomach walls that produce acids. Acid plays a major role in the production of oesophagus, stomach, duodenum ulcers. Proton pump inhibitors are responsible for the reduction of acid as it works on preventing ulcers and heal all types of ulcers present in stomach, duodenum, and oesophagus. Proton pump inhibitors are widely used method of medication in UK and US (Toh, 2014).

H. pylori can also spread through contact with contaminated water or food. The bacteria are believed to cause stomach problems when they penetrate the stomach’s mucous lining and generate substances that neutralize stomach acids. This makes the stomach cells more vulnerable to the harsh acids. Stomach acid and H. pylori together irritate the stomach lining and may cause sores or peptic ulcers in your stomach or duodenum, which is the first part of your small

• Because alkaline water is made up of smaller clumps of water molecules compared to tap water, it has the ability to pass in and out of the cells thus, keeping the body hydrated while flushing the toxins. • Those who practice alternative medicine also believe that by simply raising the body’s alkaline level, diseases and other ailments can be cured. Apparently, cancer cells cannot thrive in an alkaline environment , it is known to prevent cancer and other chronic diseases. CONS •

Weak acid like acetic acid, which do not dissociate with pH value, penerates the taste cells and can also evoke the electrical response. In this mechanism, H+ ion inhibits the potassium channels, which function in the hyperpolarization of the cells. This combination of intake of H+ ion which depolarize the cells and the inhibation of hyperpolarizing channel, together leads to polarization of membrane. The acidic stimuli activates the receptors, which cause decrease in pH and release of transmitters, this cause the excitation of afferent nerve fibers to cortex, which helps in the sour taste sensation. Primarily, acid stimuli produce a sour responese at a very low concentration, which is transduced by the chorda typani.

Medication for drug abuse is the use of medicines to dispose of drug toxins from the body. Drugs make the body full of free radicals and compounds that can damage tissues. Therefore, taking medicines (antioxidants) will neutralize these free radicals. For example, Vitamins C and E, Zinc, and Beta Carotene are good medicines to cure drug addiction. For example, if a person is addicted to hashish, doctors will give him Zinc and Beta Carotene.