Psoriatic Patient Study

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Material
The data for the present study has been collected from 167 psoriatic patients and 150 healthy controls (by taking written consent from them) and their families belonging to different areas of North India. Clinically diagnosed 150 psoriatic patients were taken who visited various hospitals of Punjab viz.: Civil Hospital, Mansa; Gian Sagar Medical College and Hospital,Ram Nagar,Banur; Raiki Hospital, Mansa; PGIMER, Chandigarh; Govt. Rajindra College and Hospital, Patiala.

Methods
The following different methods were used to observe the results of the present study:
1. Psoriasis Area and Severity Index (PASI)
2. Psoriasis Disability Index (PDI)
3. Collection of Blood
4. Elisa Test For IL-17, IL-20 and IL-22
5. BMI
6. Lipid Profile
7. Statistical
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Psoriasis Disability index (PDI)(Revised form 1999)
The Psoriasis Disability Index questionnaire is designed by Finlay in 1992 and used in adults i.e. patients overage of 16 years. It is self explanatory and can be handed to the patient who is asked to fill it in without the need for a detailed explanation. It is usually completed in 3 or 4 minutes. There are two possible alternative formats of PDI. One uses visual analogue score, the other is tick box choice.
Scoring (Visual Analogue Score)
The Scoring of each question is answered on a grade scale 0-6. If a question is left un-answered the score is taken 0.The PDI is calculated by summing the score of each of the fifteen questions resulting in a maximum of 90 and a minimum of 0. The higher the score, more quality of life is impaired. The PDI can also be expressed as a percentage of the maximum possible score of 90.
Scoring (Tick box method)
The scoring of each question is answered on a series of 4 answers, not at all (Score 0), a little (Score 1), a lot (Score 2), very much (score 3). If a question is left unanswered the score is taken is 0. The PDI is calculated by summing the score of each of the 15 questions resulting in a maximum of 45 and minimum of 0. The higher the score, the more quality of life is impaired. The PDI can also be expressed as a percentage of the maximum possible score of
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The rating of PDI score is calculated as the rating of PDI score is calculated as: 0 - 1 = no effect 2 - 5 = small 6 - 10 = moderate
21 - 20 = very large 21 - 30 = extremely
3. Collection of Blood
Blood samples of 150 psoriatic patients and 150 healthy controls were collected in BD Vacutainer by the help of medical technician. After the collection was over, blood samples were personally transported to Department of Human Genetics, Punjabi University, Patiala in an ice box. Serum was separated by

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