Pup Lab Report
We hypothesized that men with apparently clinically localized CaP harboring occult metastases would also have elevated plasma levels of components of the uPA system of plasminogen activation that would be associated with a higher risk of biochemical progression despite effective local control of disease. Therefore, to determine the relationship of the major components of the uPA system with established markers of CaP presence, invasion, metastasis, and progression, we studied pre- and postoperative plasma levels of uPA and uPAR in patients with clinically localized CaP who underwent radical prostatectomy, patients with CaP metastases to regional lymph nodes, patients with newly diagnosed CaP metastases to bone, and healthy men. The availability of pre- and …show more content…
Postoperative plasma samples were collected between 6 and 8 weeks after surgery. Blood was collected into Vacutainer CPT tubes (Becton Dickinson, Franklin Lakes, NJ) containing sodium citrate anticoagulant and centrifuged at room temperature for 20 minutes at 1,500g. The top layer, corresponding to diluted plasma, was decanted using sterile transfer pipettes and immediately frozen and stored at 80°C in polypropylene cryopreservation vials (Nalge Nunc, Rochester, NY). For quantitative measurements of serum and plasma uPA, uPAR, and plasminogen activator inhibitor type 2 (PAI-2) levels,weused specific quantitative sandwich enzyme immunoassays (American Diagnostica, Greenwich, CT). Circulating levels of uPA and uPAR were higher in patients with CaP compared with healthy controls and decreased significantly after radical prostatectomy. In patients with CaP, plasma levels of uPA and uPAR were both higher in patients with CaP metastatic to bones than in patients with metastases to regional lymph nodes, who in turn had higher levels than patients with nonmetastatic CaP. Among
Bio 655 Week 1 Lab Report
1378 Words | 6 PagesDr. Colleen Winters – BIO 655 Vishall G. Kaistha TITLE: “Recombination-Directed DNA Repair Promote Homologous Stimulating Transcription of Genes That That Preserves Genomic Integrity by MEN1 Is a Melanoma Tumor Suppressor”.
Ronald Bates Case Study
1748 Words | 7 PagesIV bolus of unfractionated Heparin or Subcutaneous injection of low molecular weight heparin (LMWH) may be used to prevent the formation of new blood clots. Nursing consideration: Require regular monitoring of activated partial thromboplasitn time (aPTT) and needed frequent heparin dose changes (Brunner and Suddarth’s, et al, 2010: 765). Fibrinolytic therapy: This therapy is given to dissolve the thrombus in the artery and restore the blood flow. There are two fibrinolytic drugs which are streptokinase and Recombinant tissue plasminogen activators (r-TPA) which includes Alteplase, reteplase and tenecteplase (Brunner and Suddarth’s, et al, 2010: 772).
Piglet 9 Lab Report
1070 Words | 5 PagesOver these 15 consecutive days our criminal justice class has watched the decomposition of 9 still born piglets, which were laid out in a specific way, with specific wounds. Piglet 10 was put into a box at the beginning of the experiment, and was not revealed until the end of it. Each piglet was in its own condition. Piglet 0 was naked in a box, Piglet 1 was naked on the grass, piglet 2 had 1st, 2nd, and 3rd degree burn all over its body, it too was laying on the grass, piglet 3 was stabbed behind right shoulder, also lying on the grass, piglet 4 had a .380 bullet would on its side, it was laying on the grass, piglet 5 was clothed on the grass, piglet 6 was naked piglet on the black top, piglet 7 was clothed on the black top, piglet 8 was suspended in the air with clothes on, and piglet 9 was suspended in the air naked. At the beginning of the experiment we hypothesized on theories we now know the answer too.
Unknown Culture Lab Report
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Pit Bull Observation Report
341 Words | 2 PagesOn 05/06/17, at 11:43am, I Deputy Warden N. Christian was dispatched to 523 S Wayne Ave on a dog on dog or cat attack, no known owner. I arrived at the location and was met by Columbus Division of Police (CPD) and complainant Raquel Fuentes. I asked what happened; Ms. Fuentes stated that she was taken part in a community event by assisting with neighborhood clean-up with her dog (small white terrier) when a brown/white Pit Bull came out of nowhere and proceeded to attack her dog. With the assistance of passerby they were able to get the brown/white Pit Bull away from Ms. Fuentes dog.
Long Lab Report
979 Words | 4 PagesShifa Sayeed can you check if this is all in past tense and if it has personal pronouns? The purpose of this experiment was to observe and thoroughly analyze how different substances of dissimilar intermolecular forces acted in different scenarios of evaporation, evaporative cooling, and boiling. In the lab, the three substances tested and compared were Acetone, Acetic Acid, and Propanol.
Unknown Lab Report
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Atul Gawande Cancer-Cluster Myth
559 Words | 3 PagesPart A: Background on Gawande and his research In 1999, Atul Gawande published a paper on the “Cancer-Cluster Myth”, which he described at the beginning of the page as, “When a dozen people in a neighborhood develop tumors, it can’t be a coincidence. Or can it?” In other words, Gawande roughly defined the “Cancer-Cluster Myth” as a conglomeration of diseases concentrated in one area of living having to have some sort of connection. Gawande was a surgeon, writer, and public health researcher who practices general and endocrine surgery at Brigham and Women’s hospital (Atul Gawande, “Bio” 2014).
Paw Flapper Lab Report
75 Words | 1 PagesFirst, place the toy in front the dog and then press start on the stopwatch. While they are trying to open the toy, take pictures. Then all you have to do is repeat the steps for the other dogs. Overall in my experiment was testing if different breeds can open the the Paw flapper (the toy). In the end the fastest dog was the Bulldog and the slowest was the Yorkie mixed poodle with poodle.
Dbq Cancer Analysis
766 Words | 4 PagesT cells are produced to attack the antigens of tumors and B cells are produced to make antibodies that are specific to the antigens of a tumor. An older individual’s immune system could react at a slower
Background And Significance Of The NCI SEER Program
534 Words | 3 PagesBackground and significance (1 paragraph, ~150 words) The NCI SEER program was created by the National Cancer Institute in the United States to collect and analyze cancer data from multiple sources to monitor trends in incidence, treatment, and survival rates. Researchers and healthcare professionals use the program's data to improve cancer prevention, diagnosis, and treatment. The information collected by the SEER Program encompasses various aspects of patient health, such as age, gender, and other demographics, as well as details about their cancer diagnosis, including the location and type of tumor, stage of the cancer at the time of diagnosis, and the initial course of treatment. Additionally, the program also tracks patient outcomes, including their survival rates based
Tn 4351 Unit 5 Lab Report
506 Words | 3 PagesTn 4351 was originally isolated from bacteroides fragilis [30] . The transposon was successfully introduced into Cytophaga succinicans, Flavobacterium meningosepticum, Flexibacter canadiansis, Flexibacter strain SFI and Sporocytophaga myxococcoides by conjugation [25]. Tn 4351carries two antibiotic resistance gene. One of the codes for resistance to erythromycin and clindamycin which is expressed in bactroides but not in E.Coli. The other gene codes for resistance in tetracycline and is expressed in aerobically grpwn E. coli, but not in anaerobically grpwn E. coli or in bacteroides.
Essay On Haemostasis
1705 Words | 7 PagesDegradation of fibrin is termed fibrinolysis. The fibrinolytic pathway is a complex physiological pathway controlled by action of a series of cofactors, inhibitors, receptors. Dysregulation of this pathway is associated with different pathologies (e.g. coagulopathies, disseminated intravascular coagulation (DIC) or congenital bleeding disorders). Degradation of fibrin is performed by serine protease plasmin, which is present in blood as a proenzyme, plasminogen, and needs to be activated by tissue plasminogen activator (tPA) and urokinase. Disturbance in haemostasis with abnormal bleeding may be caused by thromocytopenia, platelet function disorder, or defects in blood coagulation.
Albumin-Bound Formulations
1046 Words | 5 PagesClinical trials of Abraxane comparing to Taxol, showed a tolerable dose 50% larger than Taxol and improved tumor response in patients. Abraxane got approval for breast cancer and; later in 2012 and 2013; it was approved for Non-Small Cell Lung Cancer (NSCLC) and pancreatic carcinoma, respectively [82].
Biochemical Test Lab Report
1371 Words | 6 PagesBiochemical tests are the tests used for the identification of bacterial species based on the differences in the biochemical activities of different bacteria. Bacterial physiology differs from one species to the other. These differences in carbohydrate metabolism, protein metabolism, fat metabolism, production of certain enzymes and ability to utilize a particular compound help them to be identified by the biochemical tests. Gram’s stain was originally devised by histologist Hans Christian Gram in 1884. Gram-positive bacteria stain purple, while Gram-negative bacteria stain pink when subjected to Gram staining.
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