SRT1720 is a selective activator of SIRT1. Previous in vitro and in vivo studies using various cancer cell models show the role of SIRT1 either as an oncogene or a tumour suppressor gene. The oncogenic potential of SIRT1 is exemplified by studies indicating that blockade of SIRT1, like other HDACs, triggers growth arrest and apoptosis in breast, colon and lung cancers.
Decisions made in the 1850s ultimately decided the United States fate. From the election of 1856 to the Dred Scott case, the nation would become divided into two. The South was pro-slavery and supported the idea of slavery expanded into western territories, while the North opposed of the idea and was mainly against expanding slavery. Until the 1850s the nation barely balanced the slavery issue.
No matter how hard the government tried to put an end to the concerns that were rising about Rocky Flats, the Arvada community exposed the governments lies about how there was “no critical danger.” People such as Dr. Edward Martell and Dr. Carl Jonson put out the truth about Rocky Flats and the lethal radiation levels that people in the Arvada community have been exposed to. Soon after, thousands of protestors were ready to fight against the government and its secrets. Iversen also took action against the government by writing this story on Rocky Flats. She became a voice for the people who put their life on the line while working at Rocky Flats.
Some students tend to forget their teachers when they are done with school. Melissa Hoebee, a teacher who currently teaches in Southern Middle School, shares about her life in teaching and life experiences from her childhood to today. She chose to be a teacher because she wanted to help people learn in school. These life experiences and events before in her childhood helped her become the teacher she is today.
These opponents believe that the law is worth it because of the health benefits for the citizens. However, this argument has utterly no grounds because the ends should never justify the means. Forcing the citizens, who bear in mind, most of whom are adults, to do something for their own good is completely wrong. While it may be the right choice, the people should at least be able to make their own decision. The government shouldn’t have to baby their people, they can think for themselves. Removing the ability for them to have a choice strips people of their freedom, and America is built on the ideal of freedom. Adding on, the soda ban might not even have any health benefits. Referring back to Gross’ article, a nutritionist is quoted as saying, “It is not reasonable to blame or cite one product… [the proposal] produces a false sense of accomplishment in the fight against obesity.” Even health experts disagree with the ban. This mandate supposedly improves people’s well-being, but it fails at accomplishing that goal. If all the law does is strip people’s rights, and doesn’t even fulfill its main purpose, then it shouldn’t be enacted. The supposed benefits aren’t worth the trouble, which is why the law is a bad
In life some feel the need to prove something to others. That they are better, stronger, or even more intelligent. Whatever the case may be people will go through extreme measures to prove themselves. But who do we really need to prove anything to? Is it our parents? Friends? Enemies? Or is it even ourselves? Chris McCandless, deceased adventurer from “Into the Wild”, underwent many obstacles that seems highly ridiculous. Certain physical and mental challenges that could have prevented, Chris decided to do defying the chance of death or severe injury. But the real misunderstanding is who was Chris proving his manhood too?
Chris McCandless was in his early 20’s, he was the kind of that guy that wanted to learn and experience life without all of the material things. He wanted to be independent from his parents and friends so Chris did something that would be insane for most of us humans but to him, it wasn’t. He went into the wild of Alaska for months, in fact, McCandless even thought he could make it out alive at the end of his journey. As a matter of fact, he was known as being a risk taker and enjoyed being out and about in the nature side of the world. Many would believe that Chris McCandless went into the wild to purposely kill himself; however, I myself believe that McCandless did not do it purposely.
Why single out sugared sodas, they ask; obesity has many causes and contributors, not just what people drink and if sugared beverages are being targeted? Why not take stronger measures against other sources of sugar such as candy and other sweets? Pointing out that the average new Yorker goes to the movies just four times a year and buys concessions only twice, sun dee Larson a spokeswomen for amc theaters chain told the ap “we firmly believe the choices made during the other 363 days have a much greater impact on public health” (park 7)
¨Several critics questioned why the city was making proposal on sugary drinks a priority when some city schoolchildren have no physical education classes.¨ (Washington TImes) In New York, Mayor Bloomberg placed a law on the sizes of soda citizens are allowed to get. However, this caused a lot of controversy on whether the ban was good or bad. Despite the amount of people supporting the ban´s choice, the ban does have some downsides on it. It is not a good idea to limit the amount of a soda a person can purchase (or propose the ban) because it's not applying to all, it's taking rights away from people, and itś not a big deal.
“... Obesity is an issue that needs to be addressed. It is one that needs to be addressed with education, compassion, and support, not government mandates” (Stone, para 2). Prior to the middle of 2013, New York city mayor Michael Bloomberg had implemented a law that banned soda containers over the size of 16 ounces to be sold, but the ban was later repealed by the New York State Court. Essentially, the main controversy was whether the ban should have been repealed or ever created. According to Stone, by limiting people from doing something as simple as drinking certain amounts of soda, the city was going through the wrong course towards their objective. Although it may seem as though a ban on large amounts of soda would help solve many crises
What I feel I did well on this argumentative essay was my research. I had many sources that provided me with facts and statistics and they helped me to decide what side I was on. There were many sources that I did not use but that I had read through. What I struggled with was commentary. I feel that the commentary in my argumentative essay was not very strong. I am able to use discussion and debate in the future to explore/research a topic by choosing a topic and then doing research on both sides so that I can could a side to align with. Some important factors to consider while researchin are: website credibility,
Did you know that 60% of adults and one in four children in Australia are overweight or obese, making us one of the most overweight developed nations? Almost half of our population comsumes a sugary drink each day. I believe that it is about time we do something about this. With sugary drinks and weight related health problems closely linked, leading experts from the cancer Council, diabities Australia and the Heart foundation say the sugar tax would be a great solution.
Representing the wild and wonderful state of West Virginia, Nya Scott, is the current reigning Miss WV High School. Nya’s platform, Get Into Volunteering Eagerly or GIVE, allows her to relentlessly serve her community in many ways. Whether it’s feeding the hungry, marching with area representatives to encourage peace and justice on Martin Luther King day, volunteering as a buddy at "A Night to Shine", a prom for individuals with special needs, or raising awareness for BRAVE (Building Respect And Values for Everyone), the national platform of Miss High School America, Nya is ready and willing to help with a bright smile. While she is currently a sophomore at Waynesboro High School, she has earned enough credits, maintains excellent grades,
When I out grew my Shetland pony, my mother and I decided it was time to start looking for a horse for me to continue my riding career on. We had no idea at that time, that horse would be a starving, broke to only the basics, and a recent failure of a pre-purchase veterinarian exam, due to an injury to his fetlock. When we went to meet Hank, who was eventually renamed to Juble, I knew immediately that he was the horse for me, my mom wasn’t as convinced. Much like myself, my mom has a huge heart for animals, especially the ones in harmful environments, which means after minimal begging, she agreed to purchase Juble. This began the long process of helping him put on more weight, helping his swollen fetlock heal, and gaining his trust. This was six years ago, and I’m proud to say that Juble and I are two-time State
Should government units be able to regulate what we consume? No, we should not be controlled for something as little as that. There are many opinions about this topic. And many of them are relevant and logica,l but some are not.