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Salivary Construct Carcinoma (SDC)

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Intruduction Salivary duct carcinoma (SDC) is an uncommon, extremely aggressive malignancy arising from the ductal epithelium of salivary glands. Salivary duct carcinoma is an inaccurate name for this entity because other salivary tumors are also of excretory or terminal ductal origin. It was originally reported by Oscar Kleinsasser in 1968 as Speichelgangcarcinome. SDC has been also termed cribiform salivary carcinoma of excretory ducts, intraductal carcinoma, and infiltrating salivary duct carcinoma. In the 1991 World Health Organization (WHO) classification SDC has been listed as a separate categorization because of its special clinical and pathologic characteristics. Particularly, SDC is an epithelial tumor of high malignancy with formation of relatively large cell aggregates resembling distended salivary ducts. The neoplastic epithelium shows a combination of cribriform, looping and solid growth patterns, often with central necrosis, both in the primary lesion and the lymph node metastases. This extremely rare carcinoma looks like comedocarcinoma of the breast. The most important histologic attribute of this neoplasm is its similarity to ductal carcinoma of the breast. According to WHO annual incidence of all salivary gland tumors varies about …show more content…

Papanikolaou” of Thessaloniki complaining of a painless swelling in the upper right anterior region of the maxilla since two months, with a history of a rapid increase in the size in the last ten days. Intraoral examination showed a swelling approximately 4 cm in size, which was non tender, dome shaped, ulcerated extending from central incisor to second molar region. It was hard in consistency on palpation. The overlying mucosa was of the normal color as the adjacent mucosa. The mobility of teeth (11, 12, 14, 15 and 53) was observed. Clinically, there was no evidence of either cervical

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