Stenotrophomona-Maltophilia Research Paper

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CHAPTER 1 : INTRODUCTION

STENOTROPHOMONAS AND ITS EFFECT ON HUMAN BEINGS

1.1
Stenotrophomona-maltophilia is a gram negative, non-fermentive, aerobic bacteria which is usually found in aquatic environments and plant rhizospheres.
It is motile due to the polar flagella and colonizes well in MacConkey agar, which is not a generally discovered pathogen among human beings. It is resistant to many drugs and it mainly affects the nosocomial region on individuals with low immunity. Though the organism can cause infections among various tissues, organs etc, quite frequently found in respiratory tract infections. The organism has various different mechanisms for colonization and infections.

1.2
The isolation of Stenotrophomona maltophilia first …show more content…

There is still an ongoing debate about the nomenclature of this organism.

S. maltophilia does not exhibit high pathogenicity, but it has come up as one of the highly essential hospital acquired pathogen that is linked with death rates stretching from fourteen to 69% in affected people who have the condition of bacteremia.
Some of the main brought about by S.maltophilia incorporate :
• Respirational tract contagions that is highly recognized infection,
• Pneumonia and severe exacerbations of COPD (Chronic Obsrtuctive Pulmonary …show more content…

• While a study done in Saudi Arabia (2004-2009) said that most of them showed resistance to Gentamycin while >90% showed susceptibility to TMP-SMX.

Based on experiments performed :
• The results obtained by the Experiment performed in the microbiology lab by Ariya Nandakumar on 17TH March 2015, The bacteria was allowed to grow on LB agar prepared under sterile conditions and then an antibiotic was introduced to two different agar plates, and it was observed that the organism developed an inhibition zone for both Amikacin and Gentamycin.
• Amikacin inhibition zone is about 1.8 cm.
• Whereas Gentamycin hindrance zone was 2.5 cm.

The inhibition zone obtained for amikacin : 1.8cm

The inhibition zone obtained for Gentamycin is 2.5cm

2.3
From the studies, we can conclude that this organism has resistance to a variety of antibiotics but the result obtained in the microbiology lab at Bits Pilani Dubai was contradictory (for

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