Solid Dispersion Research Paper

Because salt can be dissolved in water, it is said to have high solubility. Sodium acetate also dissolves very easily in water, especially in warm water, so it has high solubility too(1). There are 2 ways to change the solubility of a solution. One way to change it is to raise the temperature because at higher temperatures most solids are extra soluble. The increase of temperature has 2 effects on almost all solutes that are solid.

This column – of a large surface area with glass or ceramic – provides ample contact between the vapor and liquid phases. A temperature gradient is formed because the head of the system is now further from the flask. Factors that affect the temperature gradient include the rate of heating and vapor removal from the system’s stillhead. Upon heating, the vapor of compound A rises, reaching a distance at which it no longer has enough energy to maintain its gaseous form; at this point, the molecules re-enter the liquid state. This process of rising up, condensation, and revaporization eventually results in vapor comprising 100% of substance A.

TLC was used to identify the actual unknown product as well as other products/reactants present in the filtered solution. The procedure was conducted by placing a TLC plate in a developing chamber that is filled with a small amount of solvent. The solvent cannot be too polar because it will cause spotted compounds on the TLC plate to rise up too fast, while a very non-polar solvent will not allow the spots to move. The polarity of the spots also determines how far it moves on the plate; non-polar spots are higher than polar ones. After spots on the TLC form, the Rf values are calculated and used to analyze the similarity of the compounds.

There was a drop in kinetic energy, so the vapor pressure inside of the can became extremely low. The drop in pressure meant that the molecules hit the sides of the can with less force and hit the sides less frequently. The pressure inside of the can was then much lower than the atmospheric pressure outside. The molecules outside crushed the can because when they hit the outside of the can, they hit it more frequently and with more force compared to the molecules inside of the

The effect of lidocaine differ from the effect of TTX is lidocaine’s effect is reversible and TTX’s effect is inreversible. The response at R2 after lidocaine application necessarily wouldn’t be zero because of the action potential. Some axons may be unaffected that cause a response to be greater than zero. Fewer action potentials are recorded at R2 when TTX is applied between R1 and R2 because TTX blocked the voltage gated channels in R2. Fewer action potentials recorded at R2 when lidocaine is applied between R1 and R2 because it blocked membrane potential and lidocaine’s effect is reversible.

So that is why the ion exchange of the pH had an effect when it was infused. 7 A. Why do you think that the renal glutamine arteriovenous difference was abolished. where ketones were infused? Glutamine that was arteriovenous abolished where ketones were infused because the renal extraction of the glutamine had to maintain negligible.

On 1/7, the Alky started to only process FCCU BB and no longer process Coker BB. Alkylation chemistry, neither likes contaminants nor diluents. Contaminants are direct acid consumers. The more contaminants in the feed, the more often the unit will be at an acid constraint. Diluents do not react in alkylation chemistry, but they take up space and decrease the effective area for isobutane and olefin to contact.

Other indeterminate random error consists in the apparatus and measuring accuracy, fluctuating at half the measurement of the lowest measurements made. This was especially important in the measurement of liquids, with +/- 0.05 millilitre differences in either the Hydrogen or the distilled water. Since these two liquids get added together, the error values add to create an overall uncertainty sum. This therefore provides the ASS and solution combined an error uncertainty of +/- 0.1mL. Due to the nature of this experiment however, this error is neglect able and the general trends form with high

This was controlled by adding a sufficient amount of distilled water to each condition, so the volume stays consistent. The temperature must be controlled because it can affect the rate of reaction, if the temperature increases then the rate of reaction would also increase. To make sure that the temperature is consistent in each condition, this experiment was conducted in one period of time in the same room. Lastly, the size of the beaker needs to be the same because reactions in smaller beakers may occur more quickly than those in bigger beakers because there is more pressure. Therefore, when doing this experiment, the sizes of the beakers were the same.

This requires the use of additional strips of welding material and time consuming repeat operations. Liquid laser adhesives are disadvantageous because they can run off of the weld site and thus may also require repeat applications. In addition, conventional laser adhesives made of protein materials, such as fibrinogen, often form rigid welds which reduce the flexibility of the welded tissues, particularly welded blood vessels. If the vessel is subjected to normal pressure fluctuations which occur during the cardiac cycle, such as the unclamping of the blood vessel or when the patient moves suddenly, the weld can rupture causing internal bleeding and related