Syphilis Case Study

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1.1. Background
Sexually transmitted infections (STIs) are a serious public health problem in developing countries, including Ethiopia (1). Syphilis is STIs caused by the spirochete Treponemapallidumand constitutes a major public health problem worldwide (2). Syphilis is an important cause of morbidity and mortality in pregnancy and it is one of the greatest public health challenges (3). Pregnant women are sexually active and at risk of sexually transmitted disease, including syphilis. Syphilis remains a major cause of reproductive morbidity and poor pregnancy outcomes in developing countries. In prenatal care Screening and treatment for syphilis is routine and is a cost-effective intervention (4). Fetal infection is a result of hematogeneous
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Statement of Problem
STIs are widespread in the developing countries and constitute a major public health problem in sub-Saharan Africa. Syphilis has re-emerged as a global public health issue and World HealthOrganization (WHO) estimated that approximately 12 million new syphilis infections occur each year worldwide, many of which go untreated especially in less developed countries.
Globally, about 1 million pregnancies are affected each year by syphilis due to maternal infection, and because of these about half of the pregnancies result in stillbirth or neonatal death more recently; there has been a resurgence of syphilis(6)

Testing for syphilis in pregnancy and labour is medically indicated because of the potential risk for congenital infection and fetal loss. Syphilis has also acquired a new potential for morbidity and mortality through association with increased risk for HIV infection(7)
Maternal syphilis is estimated to contribute to 29% of prenatal deaths, 11% of neonatal deaths, and 26% of stillbirths around the
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Therefore, it is better to asses and understands the syphilis epidemiology among pregnant women, the sero prevalence of syphilis and socio-demographic correlates of this infection at Gondar university teaching hospital. A study of the epidemiology of syphilis in pregnant women booking for antenatal care in those attending public sector including hospitals antenatal clinics provides the motivation for further study and a follow up pilot study furthermore this study was provides information critical to the design appropriate intervention strategies to reduce the burden of syphilis in pregnant

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