Presenting clinical pharmacology and therapeutics: a problem based approach for choosing and prescribing drugs. Br J Clin Pharmacol. 1993; 35(6):581–586 4.Denig P, Haaijer-Ruskamp FM. Therapeutic decision making of physicians. Pharm World Sci.
The pharmaceutical industry, despite several regulations set by the food and drug administration, is a free market economy. Meaning, the pharmaceutical sector lacks government regulation and has control over the prices of specialty drugs desperately needed by the public. Therefore, the pharmaceutical industry being a free market negatively affects the
Introduction: As the food enters the mouth, it interacts with saliva and taste receptors which are located in the oval cavity and other locations in the human body. Taste receptors plays a vital role in the sensation of taste. It maintains nutrition for the body and contributes in the identification of toxin subtances. The combination of different types of receptors helps in perception of the taste of substance inside the mouth. In gustatory system, the taste receptors cell are found in taste buds.
Figure 15: FTIR spectra of pantoprazole sodium+kollicoat MAE 30DP Drug-excipient compatability studies: FTIR In the FTIR spectra of pure drug and different polymers it is observed that the peaks of major functional groups which are present in spectrum of pure drug are observed in combination of drug and polymers. There was no appearance or disappearance of any characteristics peak in the FTIR spectrum of Optimized formulation. This shows that there is no chemical interaction between the drug and the polymers used .The presence of peaks at the expected range confirms that the materials taken for the study are genuine and there were no possible interactions occurred. 7.1.2 PREFORMULATION CHARACTERISTICS Table 23: Preformulation of powder blend of pantoprazole sodium core tablet Formulation code Angle of repose Bulk density (gm/cm2) Tapped density (gm/cm2) Hausners ratio %compressibility C1 25.7±0.03 0.34±0.02 0.42±0.03 1.24 19.04±0.01 C2 26.8±0.01 0.36±0.02 0.45±0.05 1.26
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Their taste varied from acidic to tart to bitter to nutlike. Pollan believes we have lost our sense of sweetness by latching onto fake tastes that resemble what our ancestors might have called sweet. Chemicals in food have taken away our ability to recognize a sweet taste. Sweetness has been domesticated just like the
The taste, smell antimicrobial properties of these substances are derived from compounds known as phytochemicals (secondary metabolites) present in the substance that inhibit growth of bacteria (Avato et al. 2002). The presence of a benzene functional group and sulfur may be an important component of the antimicrobial mechanism (Agabalogun, L et al). Presently, approximately 80% of the world population relies on botanical derived medicines as they are considered safe, free of side effects, effective against bacterial ailments and do not pose threat of bacterial resistance (Hora and Nair.1944). In this experiment, the antimicrobial properties of the powdered forms of three widely used Indian spices: Turmeric (Curcuma longa), Indian Lilac/Neem (Azadirachta indica), Ginger (Zinhiber officinale), Asafetida (Gumm oleoresin) was further investigated.
The trademark caramel color of the popular colas may be aesthetically pleasing but its effects are purely evil; 4-methylimidazole is a carcinogen found in the brown food coloring. [ref]Smith, Tyler JS, Julia A. Wolfson, Ding Jiao, Michael J. Crupain, Urvashi Rangan, Amir Sapkota, Sara N. Bleich, and Keeve E. Nachman. "Caramel Color in Soft Drinks and Exposure to 4-Methylimidazole: A Quantitative Risk Assessment." PloS one 10, no. 2 (2015): e0118138.