The Importance Of Clinical Research
INTRODUCTION Clinical research are known as the research being done in order to design or to find out new interventions which can be useful to human population by curing their disease. Usually clinical research are done to find new drugs or chemical entities which producing the safe and effective therapeutic outcome to the human population who using it by improving their health conditions. It is basically to find safe and effective ways to prevent, diagnose or treat particular disease in human beings. Clinical research involves clinical trials where the new findings or interventions will be tested for safety and efficacy in humans. For each research that have been done particularly involving the drug entities should undergoes clinical trials …show more content…
All these steps need to be followed in a clinical research in order to release one drug into the market, so that it has the best therapeutic effect and less adverse effects and also proven that it is highly safe to be used in human population for particular disease conditions [1]. For one particular clinical research to be conducted, there a lot of procedures need to be followed according to the rules and regulations. The researchers also must follow the ethics of the clinical research when investigating the effect of new drug on the human beings. The ethical become one of the important part in clinical research or clinical trials as the involvement of humans which can also develop the high risk of having particular disease or any other harmful effect form the trials or research. So it is very important, for the researcher to take all the ethical requirements into consideration before investigating on the human …show more content…
The rules also lead to the evolution of clinical trials. The first clinical trial was conducted by Ambroise Pare, famous surgeon in 1537 for the treatment of battlefield wounded soldiers. He had applied the conventional treatment which is the oil to the wound of the soldiers while due to the lacking of the oil, he had applied the unconventional treatment which is digestive medicaments made of yolks of eggs, oil of roses, and turpentine as the lack of oil. The result shows that those who have treated with the digestive medicament showing better improvement than others with conventional
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646 Words | 3 PagesLikewise, the best treatment should not refer to local treatment standards, but the best standards available to maximize the beneficence and justice applied to participants already undertaking the burden of participating in a clinical trial. Unfortunately, ethical principles can sometimes be neglected due to competition in the field and the increase of regulations. This has resulted in some ethically questionable trials based in third world countries that violate justice, autonomy, and beneficence to obtain faster results. Harold Varmus and David Satcher’s perspective on what standards and guidelines should be implemented in clinical trials in third world countries differs from that of Angell’s arguments. They make the argument that compared to other approaches, a placebo is the most justified way to obtain clear and rapid results from clinical trials regardless of what treatments may currently be available.
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