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In this phase, a small unstable actin filament called the ‘nucleus/seed’ is formed. The nucleus is made when one actin monomer (G-actin) interacts with two other monomers and forms a triple monomer attached actin filament. Only when this nucleus is formed, the polymerization can proceeds to the next step. In the Extension phase, the actin monomers are added to the nuclei and the filament (F-actin) increases in the length. The monomers are added
Cell Biology BI309 Mini-Review 1 Title: Dynein Motor Proteins In order for eukaryotic cells to be motile they use motor proteins that are propelled by ATP. There are three classes of motor proteins; myosin, kinesin and dynein. Dynein is the motor protein to be discussed in detail for this review. Dynein is a large and complex motor protein found in microtubules of cilia and flagella that causes movement due to the conversion of Adenosine Triphosphate(ATP) which is a form of chemical energy to mechanical energy i.e. movement.
Eikelboom, J. S. (2012). Aspirin. Circulation, e438-e442. Fessenden, R., Fessenden, J., & Feist, P. (2001). Organic Laboratory Techniques, 3rd Edition.
Presenting clinical pharmacology and therapeutics: a problem based approach for choosing and prescribing drugs. Br J Clin Pharmacol. 1993; 35(6):581–586 4.Denig P, Haaijer-Ruskamp FM. Therapeutic decision making of physicians. Pharm World Sci.