The Importance Of Nucleotides
Nucleotides are the energy currency in a metabolic transaction. Nucleotides are the organic molecules that serves as the monomer units or building blocks of nucleic acids (the basic structural unit of nucleic acid) like DNA and RNA. Nucleotides consist of sugar, nitrogenous base, and phosphate. The nitrogenous bases found in nucleotides include adenine (purine), guanine(purine), thymine (pyrimidine), cytosine
(pyrimidine), and uracil (pyrimidine). The bases adenine, guanine, and cytosine are found in both ribonucleotides and deoxyribonucleotides. Thymine is almost always found in deoxyribonucleotides. Uracil is found primarily in ribonucleotides and rarely in DNA, but does appear as a deoxyribonucleotide intermediate in thymidine metabolism. Nucleotides form a part of many coenzymes and serve as donors of phosphoryl groups (e.g. ATP or GTP), of sugars (eg, UDP- or GDP-sugars), or of lipid (e.g. CDP-acylglycerol). Regulatory nucleotides include the second messengers cAMP and cGMP, the control by ADP of oxidative
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The building blocks of nucleotides are heterocyclic ring base which maybe the derivatives of either pyrimidine or
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