Teeth Synthesis

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Teeth are strategically placed at the entrance to the oral cavity and the gastrointestinal system. They are subjected to various physical, chemical and mechanical insults in the course of a single day yet they are expected to survive and function. We are witnessing an increase in life expectancy in recent years. It is important to retain all our faculties to enjoy quality living. Hence a lot of research is focused on preventing damage to existing body parts so that they may serve us long and well. Damage to tooth enamel from cough lozenges is an unexpected complication with irreversible consequences. Tooth enamel is the hardest substance in the human body and has a unique combination of hardness and fracture toughness that protects teeth…show more content…
High Performance/Pressure Liquid Chromatography is a technique in analytical chemistry used to separate, identify, and quantify each component in a mixture. It works on pumps to pass a pressurized liquid solvent, containing the sample mixture, through a column filled with solid adsorbent material. Each component in the sample interacts slightly different with the adsorbent material, causing different flow rates for the different components.7 This leads to the separation of the components as they flow out the column. The components of the sample mixture are separated from each other due to different degree of interaction with the absorbent particles. The pressurized liquid is referred to as "mobile phase, a mixture of solvents (e.g. water, acetonitrile and/or methanol). Its composition and temperature play an imp role in the separation process by influencing the interactions which occur between sample components and adsorbent. These interactions are physical in nature, such as hydrophobic (dispersive) or dipole–dipole and ionic or most often a combination. The choice of mobile phase components, additives (such as salts or acids) and gradient depends on the nature of the column and sample components. Often a series of trial runs are essential with the sample in order to find the HPLC method which gives adequate separation. The extent or degree of separation are mostly determined by the choice of stationary phase and mobile

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