Introduction Thrombocytosis is when you have too many platelets (thrombocytes) in your blood. Platelets are parts of blood that stick together and form a clot (thrombus) to help your body stop bleeding. Some conditions that cause inflammation, such as cancer, may trigger your body to make more platelets than normal. There are two types of thrombocytosis. Primary or essential thrombocytosis happens when abnormal cells in the bone marrow make too many platelets.
Some causes for secondary thrombocytosis are von Willebrand disease, and cancers. Is thrombocytosis related to any other diseases? No it is not but there are other diseases out there that are causes for secondary thrombocytosis. The von Willebrand disease is one of the causes and different types of cancers are also causes. The types of cancers that can cause secondary thrombocytosis are lung, gastrointestinal, and ovarian.
Thrombosis Formation Thrombosis is the formation of a thrombus within the vascular system. Development of thrombosis after vessel wall injury is characterised by the deposition of platelets, tissue factor and fibrin. A thrombus is a solid or semi-solid mass, which consists of aggregated platelets, that form a platelet plug and a mesh of cross-linked fibrin protein. The formation of a thrombus is a healthy response to blood vessel injury intended to prevent blood loss, and is the first step in restoring haemostasis. Blood vessel damage can also be caused by the interaction between a foreign material (medical device) and the endothelium lining of the vessel.
Blood clotting occurs during an injury to a blood vessel, the blood and platelets bind together to from a jelly like substance called clot. C. Platelet, that play a fundamental role in this process also have deadly disorders. 1. Thrombocytopenia is the over production of platelets 2. This disorder leads to too much blood clotting 3.
INTRODUCTION A thrombus or a blood clot is the final product of the blood coagulation which brings in hemostasis. Clotting is essential and it is life saving to arrest bleeding during trauma, surgery etc. it is well known when thrombus is not formed as in the case of hemophilic they can bleed to death. So that substantiates the necessity of clotting. However blood clots can also form abnormally obstructing the blood flow through the blood vessels causing myocardial infarction, brain stroke, gangrene of the extremities and other medical problems.
THROMBOSIS When a blood vessel is injured, the cells of your blood bond together to form a blood clot. The blood clot helps you stop bleeding. Blood clots are made of a combination of blood cells, platelets (small sticky cells that speed up the clot-making process), and fibrin (protein that forms a thread-like mesh to trap cells). Doctors call this kind of blood clot a “thrombus.” Blood clots are good when they help seal a cut to stop bleeding. But sometimes, a blood clot can form when it is not needed.
Platelets or thrombocytes (thromb- + -cyte, "blood clot cell"), are a component of blood whose function along the coagulation factors is to stop bleeding by clotting blood vessel injuries. Platelets are biconvex discoid (lens-shaped) structures and 2–3 µm in greatest diameter, have no cell nucleus .  They are fragments of cytoplasm that are derived from the megakaryocytes of the bone marrow and then enter the circulation.  Structurally the platelet can be divided into four zones, from peripheral to innermost: I. Peripheral zone - is rich in glycoproteins required for platelet adhesion, activation, and aggregation.. II.