Peake M, Whiting M. Measurement of Serum Creatinine – Current Status and Future Goals. Clin Biochem Rev 2006; 27: 173–184. 2. Kaburaki J, Yamada M, Kamikawara M, et al. In vivo and in vitro positive interference by cefpirome in measurement of serum creatinine by the Jaffe method.
Development and method validation using HPLC for assay of Ziprasidone capsule. International Journal of Pharmaceutical sciences and Research .20112(9):2325-2327 20. T.Kaleemullah , Mansur Ahmed, Hemany Kumar Sharma, KVSN Raju ,and M.Narendra Kumar. Development and validation of gas chromatography method for low level detection of residual methyl chloride, ethyl chloride and isopropyl chloride in Ziprasidone hydrochloride. Der pharma chemical
It can also be useful to the researcher that evaluates the feasibility of utilizing an intrinsic or in-situ bioremediation of a target contaminant by evaluating the biodegradability potential of contaminants. 2. What is Push-Pull Tests? Push-pull tests are conducted by “pushing” a test solution of known concentration into the saturated zone of an aquifer via a well. The samples were then “pulled’ out of the aquifer via the same well over time to obtain information on the magnitude and rate of the biodegradation as shown in Figure 1 (Istok, Humphrey, Schroth, Hyman, & O'Reilly, 1997).
Response surface methodology (RSM) is used for optimization of drug delivery systems which involves the use of various types of experimental designs, generation of polynomial relationships and mapping of the response over the experimental domain to select the optimum formulation (24–26). Amongst various experimental designs, the central composite design has been commonly used for designing and optimization of different pharmaceutical formulations and processes (27-29). This technique is more flexible, effective and provides large extent of information on experimental variable effects. In addition, it requires minimum number of experimental runs and
Aim:2 Expanding the Application of Conductive Polymer for Solid Phase Extraction 2.1 (New Direction) Application of Polypyrrole based Conductive Polymer Coating Material for Extraction, Determination and Quantification of Active Ingredient in Personal Care Products 2.1.1 Introduction Triclosan is commonly used in personal care and household products such as shampoo, toothpaste, soaps, detergents, skin care creams and lotions because of its antimicrobial properties. As per US food and drug agency (USFDA) the typical concentration of triclosan should not exceed 0.3% (w/w) of product weight42. The reports suggest that triclosan is transported to municipal wastewater treatment plants through domestic sewage and finally discharged in aquatic environment from wastewater effluent43. The
(Table 2). In the same medium NBRIP used to isolate phosphate solubilizers, values ranging from 31.5 to 519 μg.mL-1 were obtained [41] and in the present study the observed amounts were even higher (26 to 1.735 μg.mL-1 (table 3). A positive correlation between in vitro phosphate solubilization activities of Pseudomonas sp. (LG) with an increase in P content in bean plants inoculated with this bacterium has been observed [42]. In our work, Pseudomonas spp.
Ltd. (Mumbai. India). Methanol, sodium hydroxide and glacial acetic acid were purchased from Merck Limited (Mumbai, India). Human cervical carcinoma cell line (HeLa) was obtained from National Center for Cell Science (NCCS) (Pune, India). 3-(4,5-dimethylthiazool-2-yl)-2,5-diphynyl tetrazolium bromide (MTT) and Dulbecco’s PBS (pH 7.4) were purchased from HiMedia Lab.
Also, this solid dispersion can be filled in capsules and capsules are then coated with enteric coating polymers. (Singh et al .,2013) prepared colon specific matrix tablets of Azathioprine and concluded that katira gum successfully target the drug in the colon by pH dependent approach. (Darwheka et al ., 2013) prepared colon specific satranidazole tablets using guar gum, pectin ,xanthan gum and concluded that guar : xanthan gum is in combination at 2:1 can be developed to deliver the drug in colon . Singh Rakesh formulated colon specific matrix tablets of metronidazole using ionically cross
in accordance with ISO 13781. 4.1.4.1.2 Reagents for oxidative degradation For oxidative degradation, a) water and hydrogen peroxide, e.g. 3 % hydrogen peroxide solution, Pharmacopoeia grade b) Fenton´s reagent 4.1.4.1.3 Other test solutions Other test solutions for a specific polymer or a specific application site may be chosen. 4.1.4.2 Container chemical grade glassware, polytetrafluoroethylene or polypropylene containers in an enclosed system shall be used Controls shall be used in order to determine contaminants from the container 4.1.4.3 Balance The balance used to determine mass loss shall be capable of weighing the initial sample mass with the precision required The precision and standard deviation of the method of the determination of mass loss shall be stated in the test report. 4.1.4.4 Drying apparatus Any apparatus able to dry the test samples to constant mass without contamination or loss of volatile degradation products shall be used.
The number of multiple drug resistant strains are considered. This study showed that Ginger extract has an antibacterial effect. The phytochemical constituents were observed in Zingiber officinale. The outcome of their study was that the antimicrobial activity of the extracts obtained from ginger was useful and it can be relevant in different domain of research specifically in the pharmaceutical and food industries. (Antimicrobial Activity of Zingiber Officinale (Ginger) Extract Against Some Selected Pathogenic Bacteria, Akintobi OA, Onoh CC, Ogele JO, Idowu AA, Ojo OV, Okonko