Varicella-Zoster Research Paper
aricella-zoster virus (VZV) is a ubiquitous human alpha- herpesvirus, which causes varicella (chicken pox) and herpes zoster (shingles). Varicella results from primary VZV infec- tion; it is a common childhood illness associated with fever and a generalized pruritic vesicular rash. As is characteristic of the alphaherpesviruses, VZV establishes latency in cells of the dorsal root ganglia after primary infection. Herpes zoster is a localized, painful, vesicular rash involving one or adjacent der- matomes and caused by VZV reactivation. The incidence of herpes zoster increases with age or immunosuppression.
Historically, the relationship between the etiologies of vari- cella and herpes zoster was first suggested by von Bo ́kay in 1892, from the observation that young children often devel- oped varicella after exposure to an adult with herpes zoster (249). Transmissibility of the agent was demonstrated by inoc- ulating children who had no history of varicella with fluid recovered from herpes zoster lesions; these children developed varicella, and secondary
…show more content…
Goodpasture and Anderson detected multinucleated giant cells in a human skin/ chorioallantoic membrane culture system infected with herpes zoster lesion fluid in 1944 (107), and infectious VZV was isolated in tissue culture by Weller and Stoddard in 1953 (258). Knowledge about the molecular virology of VZV and mecha- nisms of pathogenicity has grown during the past two decades. The complete VZV genome has been sequenced, the infectiv- ity of intact VZV DNA has been demonstrated (39, 53), and, most recently, infectious virus has been produced from cos- mids spanning the genome (39). Antiviral agents that modify the severity of varicella and herpes zoster have been devel- oped, and a live attenuated varicella vaccine that protects against primary VZV infection is now licensed for clinical use (3, 245, 260,
Dr. Leonard Hayflick During The 1946 Polio Epidemic
701 Words | 3 PagesThe Rubella virus was infecting millions of people, especially pregnant women. When a pregnant woman is infected by Rubella, a miscarriage or a stillbirth will happen to the fetus. If the fetus makes it to birth, it will have extreme birth defects. Stanley Plotkin was a man who discovered a vaccination for the Rubella virus. He worked in the same biomedical research center as Dr. Hayflick, The Wistar Institute.
Boston Smallpox Research Paper
112 Words | 1 PagesBoston Smallpox Epidemic of 1721: When smallpox broke out in Boston, Cotton Mather introduced an untested medical procedure called “inoculation”, which would introduce a small amount of the virus to a patient, in hoping they would become immune to it. Many were opposed to it, even though it worked. Many people died due to the epidemic. 31. Common Sense: Thomas Paine wrote a book called "Common Sense", it sold more than 150,000 copies when the population was only 3 million.
Mmupv1 Infection Lab Report
675 Words | 3 PagesA carcinoma was developed in a female outbred nude mouse skin site A cutaneous lesion grew at the foreleg of one infected animal at 9.5 months post-infection (Fig. 2A). Histological analysis showed that this lesion had progressed to malignancy (Fig. 2B). The lesion was MmuPV1 positive (Fig. 2
Shingles Disease Research Paper
63 Words | 1 PagesShingles also has other names such as Zoster, Herpes zoster, or Zona. It is a viral infection that causes a skin rash to the injured person. It is the same virus that infects person and causes him to chickenpox disease. There are some ways to treat people with Shingles disease, which has many symptoms that can evolve and become more dangerous if
What Are The Rhetorical Patterns In Out Of The Wild
1625 Words | 7 Pages“An idea is like a virus. Resilient. Highly contagious. The smallest seed of an idea can grow. It can grow to define...or destroy you.”
SOAP Evaluation
1621 Words | 7 PagesRetrieved from https://digitalbookshelf.southuniversity.edu/#/books/9780803641242/ Medscape. (2016). Herpes Zoster. Retrieved from http://emedicine.medscape.com/article/1132465-overview Solomon, C., & Cohen, J. (2013). Herpes zoster.
Impetigo Bacterial Infection: Case Study
1137 Words | 5 PagesThe infected individual will develop vesicles or lesions over the body that are fluid filled and have a high probability of rupturing. Patients will typically present with hundreds of lesions or vesicles. The length of time for vesicle formation is 4-5 days (Soman & Madan, 2013). Chicken pox can be transmitted airborne or through direct contact with the fluid present in the vesicles (Soman & Madan, 2013). Patients with chickenpox are considered infectious48 hours prior to the vesicular rash (Soman & Madan, 2013).
Gardasil Causing Girl's Death Summary
451 Words | 2 PagesCerebral vasculitis is a severe form of blood vessel inflammation in the brain that can lead to severe autoimmune disorders and even death. The HPV-16L1 antigen are particles that represent a genetic fingerprint of the Gardasil vaccine. These particles are causing the serious side effects, and death in some cases, of some of the girls that were given the vaccine. A postmortem assessment proved HPV-16L1 was inside the brain tissue of two girls who had died shortly after receiving Gardasil.
Case Study: Assisted Living
133 Words | 1 PagesOn March 15, 2016 at 4:34 am, I was notified by Elisha Smalls that she had discovered red spots on her arms and mid back and had an itch. The employee was instructed to leave the facility and see her physician as soon as possible and to follow-up regarding the visit. At 11:14am, the employee called back and stated she had chicken pox and was in contact a resident in ALF that had shingles. It was discovered that the employee di d work with the resident on 02/24/2016 and 02/25/2016.It was discovered on February 24, 2016; a resident in Assisted Living did exhibited signs and symptoms of possible shingles. The resident was seen by the Nurse Practitioner, Jody Eblen for a rash with pain, the resident was started treatment with antibiotics on
Informative Essay On Herpes
1227 Words | 5 PagesYou can find herpes in the smallest part or area of your body. It can be spread from person to person if you have that type of disease. Unfortunately Twanda didn't know all she knew was that she was breaking out
Monologue Tribe
1394 Words | 6 PagesHe had muscle pains, headache, and vomiting. I realized that he started showing symptoms of smallpox that I had. 4 days later, small red spots began to appear in his mouth, tongue, and throat. A day or two after that, red bumps began to appear on his
Varicella Research Paper
1528 Words | 7 PagesThe varicella vaccine is a safe and effective way to prevent the disease. Currently there are three licensed VZV-containing vaccines in the United States: varicella vaccine, combination measles-mumps-rubella-varicella vaccine (MMRV) and herpes zoster vaccine. The Varicella vaccine is a live-attenuated viral vaccine for persons 12 months of age and older (“Varicella”). In September 2005, the FDA licensed the combined live-attenuated MMRV for persons 12 months through 12 years of age. The herpes zoster vaccine was approved by the FDA in May 2006 for people 60 years of age and older which was later changed in 2011 to 50 through 59 years of age (“Varicella”).
Summary Of The Hot Zone By Richard Preston
580 Words | 3 PagesFrom the gentlest to the most fatal, the Ebola trio is ranked as Marburg, Ebola Sudan, and Ebola Zaire. However, in a quest to determine a new strain of Ebola, scientists discover a harmless-to-humans but fatal-to-monkeys agent known as Ebola Reston. Marburg virus can affect humans like nuclear radiation by virtually damaging all the tissues in their bodies. Ebola and Marburg are both viruses that cause hemorrhagic fevers, organ failures, brain damage, and death. AIDS, a virus emphasized alongside the Ebolas, is stated to be the most environmental disaster of the twentieth century (page 227).
Virology Personal Statement
651 Words | 3 PagesIt was never a question for me whether to pursue a career in research. The question was in what area. The answer to that formed over the course of my secondary studies as well as my university course. My interests comprised of Cell and Molecular Biology, but lately I have been interested in Virology the most. Even before I had a satisfying idea of what the study of viruses comprises, I found it very fascinating.
Tobacco Mosaic Virus Research Paper
1070 Words | 5 PagesIt is constituting of 2130 coat protein molecules and a single-stranded RNA of 6400 bases. It’s rod like structure is assembled into a helix using the coat proteins and they form a hairpin structure(5,6). The protein monomer has 158 amino acids and assembled into four main alpha-helices that are joined to the central axis of the virus. The virion is 18 nm in width and 300 nm in length and a 4 nm core inside it(in the central part) (5,6,7). The TMV genome consists of 6.3-6.5 kb single stranded RNA and has a 3’ end which a t-RNA like structure and the 5’ end cap is methylated(8).
More about Varicella-Zoster Research Paper
Dr. Leonard Hayflick During The 1946 Polio Epidemic
701 Words | 3 PagesBoston Smallpox Research Paper
112 Words | 1 PagesMmupv1 Infection Lab Report
675 Words | 3 PagesShingles Disease Research Paper
63 Words | 1 PagesWhat Are The Rhetorical Patterns In Out Of The Wild
1625 Words | 7 PagesSOAP Evaluation
1621 Words | 7 PagesImpetigo Bacterial Infection: Case Study
1137 Words | 5 PagesGardasil Causing Girl's Death Summary
451 Words | 2 PagesCase Study: Assisted Living
133 Words | 1 PagesInformative Essay On Herpes
1227 Words | 5 PagesMonologue Tribe
1394 Words | 6 PagesVaricella Research Paper
1528 Words | 7 PagesSummary Of The Hot Zone By Richard Preston
580 Words | 3 PagesVirology Personal Statement
651 Words | 3 PagesTobacco Mosaic Virus Research Paper
1070 Words | 5 Pages