The only sign the baby may have of Spina Bifida is an abnormal tuft or clump hair or a small dimple or birthmark in the skin at the site of the spinal malformation (NIH). Spina Bifida have a few symptoms but it depends on which type and the intensity of the disease in the baby. Many of the symptoms the baby will experience are: loss of bladder or bowel control, partial or complete lack of sensation, partial or complete paralysis of the legs, weakness of the hips, legs, or feet of the newborn. Other symptoms can be: abnormal feet or legs, such as clubfoot and buildup of fluid inside the skull (Hydrocephalus). Spina Bifida can be diagnosed in three different ways such as: AFP test, ultrasound and amniocentesis.
The cervix is one of the least common sites in genitourinary tract.We report a case of Cervical Rhabdomyosarcoma who was misdiagnosed as Vaginal RMS and was started on chemotherapy. We had to do an emergency excision of the mass,when she developed excessive bleeding per vaginum. Keywords Embryonal Rhabdomyosarcomas,Cervical Rhabdomyosarcomas, Background Rhabdomyosarcomas are malignant skeletal muscle tumors and account for about 50% of soft tissue sarcomas in children. The Intergroup Rhabdomyosarcoma Study Group divided it into three major histologic subtypes: Embryonal(ERMS), alveolar, and undifferentiated. The most common sites include head and neck(35%),extremities, trunk, retroperitoneum.
A major problem that most couples face today is Infertility. Infertility is a medical condition where a couple fails to conceive or reproduce within the following 12 months after intercourse or unprotected sex. The medical condition of Infertility is often preconceived to occur primarily due to disorders in the reproductive system of the female partner, which is completely false as the disorders in the reproductive system of the male partner are equally responsible for infertility (who.int). There are several causes and risk factors of infertility in both genders. The most common cause for infertility in males is ‘Sperm Abnormalities’.
Another mechanism of action is the altering of expression and phosphorylation of member of the bcl-2 family of proteins, docetaxel associate with the phosphorylation and inactivation of bcl-2 protein, members of the bcl-2 family are highly conserved proteins which regulate apoptosis. Docetaxel can display a wide spectrum of anti-cancer activity in preclinical trials. The clinical trial has shown that docetaxel is effective against hormone refractory prostate
The pathophysiology of a goiter in hypothyroidism would occur to a disruption of Thyrotropin-Releasing Hormone/Thyroid Stimulating Hormone. An unbalance in these hormones would cause changes in the function and structure of the gland. In the setting where there isn’t a sufficient amount of Thyroxin synthesized by the gland, there is an increase in TSH production. Over production of TSH causes hyperplasia of the gland just to match normal thyroid levels. This would then cause a goiter to form.
Approximately half of those who suffer from this condition develop fevers; however, nausea and vomiting are not common (Uphold & Graham, 2013). The condition is also typically associated with asymptomatic urethritis when it is transmitted sexually and may eventually lead to a gradual unset of testicular pain, tenderness, dysuria and urethral discharge (Uphold & Graham, 2013). Chronic epididymitis is characterized by symptoms lasting for greater than six weeks (Uphold & Graham, 2013).
This disease is often presented in elderly because there cellular Immunity is reduced. There are many important facts associated with the Herpes Zoster virus which is causation, signs & symptoms, Treatments available, organ system involved and other important historical facts associated with this disease. In the United States there are about 1 out 3 people who develop shingles and there is about 1 million cases involving shingles every year.
They noted that his platelets were decreased in number, larger than normal, and lacked the ability to adhere to blood vessel walls (Lanza,2006). This resulted in a prolonged bleeding time. The hematologists named the disorder "Dystrophie thrombocytaire-hémorragipare congénitale" (Hemorrhagiparous thrombocytic
Currently the most accepted hypothesis is a vascular disruption causing a hypoxic/ischemic insult to the brainstem in the first trimester23, 24. This can be caused by various teratogens evoking uterine contractions. The following teratogens have been described including: gestational hyperthermia 25, 26, chorionic villus sampling 27, abuse of benzodiazepines 28, alcohol 25,cocaine29, thalidomide 30, ergotamine 31 or self-induced abortion – misoprostol 32. Hypoplasia or aplasia of the nuclei can also be caused by genetic mechanisms 1, but because the majority of Moebius syndrome cases are sporadic, genetics play only a minor role. So far three different chromosomal regions for familial Moebius syndrome have been reported: MBS1 (OMIM 157900, 13q12.2-q13) 33, 34, MBS2 (OMIM 601471, 3q21-q22) and MBS3 (OMIM 604185, 10q21.3-q22.1) 35, 36.
Of course, the condition will most likely involve a heart problem, which is discovered at birth, along with a webbed neck, chest deformities, many birth marks, also known as café-au-lait spots, and a short stature. The features of this syndrome are not fully known, considering the fact that there are numerous characteristics and no two infected individuals have the same exact features. Like in most other disease cases, there are lists of more minor symptoms that can occur in an individual. In infants and newborns, feeding problems are present, due to a poor sucking reflex. Behavioral problems and developmental delays can occur, which causes the individual to achieve milestones slower, such as sitting and walking.
Cystic Fibrosis Cystic Fibrosis is a genetic disease that affects the lungs and the digestive system. Because this disease limits breathing ability, it is a life-threatening disease. In the United States alone, 30,000 people have cystic fibrosis and 1,000 new cases of CF are diagnosed every year. Over half the of the people with CF are over the age of 18. (About Cystic Fibrosis) Cystic Fibrosis is caused by a mutated gene that changes the protein that controls the salt in and out of the cell.