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Zebrafish: An Ideal Model

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Zebrafish is an ideal model for evaluating the drug development, toxicity testing of nanoparticles and high throughput screening of lead molecules in pharmaceutical and biomedical sciences. Furthermore, due to transparency, zebrafish embryo have been extensively studied to evaluate genetic manipulations [21]. Zebrafish embryos were used to investigate the developmental toxicity of both normal and drug coupled AuNPs. The survival rate was expressed as the number of embryos that had hatched by 96 h post fertilization, as compared with the control group [Fig. 5A (i)].The mortality level was indicated by the dead embryos 96 h post fertilization as compared to the control group [Fig. 5A (ii)]. Both survival rate (%) and mortality rate (%) studies

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