Anovulation Essays

First discovered in 1935 by Stein and Leventhal, polycystic ovarian syndrome (PCOS) is a complex endocrine and metabolic disorder that is characterized by menstrual irregularity, subfertility and infertility, clinically obvious hyperadrogenism, and metabolic dysfunction in women (Azziz, 2015). Although the etiology of this complex condition is unclear, the prevalence is about 20-40% in women who have mothers and sisters with PCOS, strongly suggesting a genetic association (Azziz, 2015). B.L. presented

women in 1961 and was approved by the Food and Drug Administration (FDA) in 1967(102) It was approved for marketing in 1967 under the brand name Clomid. It was first used to treat cases of oligomenorrhea but was expanded to include treatment of anovulation when women undergoing treatment had higher than expected rates of pregnancy.(23) Clomiphene was initially discovered to be effective in the treatment of polycystic ovarian (PCO) disease and other forms of

Nearly 5% to 10% of females are affected with PCOS. Are you wondering what PCOS is? PCOS (Poly Cystic Ovarian Syndromes) also known as hyperandrogenic anovulation is a problem in which womens hormones are out of balance. It can cause problems with your periods and make it difficult to get pregnant. There are many signs to look for when you think you may be affected by PCOS. Some of the symptoms are but not limited to: Acne, weight gain and trouble losing weight. Extra hair on the face and body.

intricate genetic condition where the prevalence of obesity among women with PCOS is higher than that of age-matched, healthy women without this syndrome (Yildiz et al., 2008). They have characteristic features like hyperandrogenism, chronic oligo/ anovulation, central dysregulation of gonadotrophin secretion, obesity, hirsutism and menstrual abnormalities. β-endorphins in PCOS patients were detected in the pancreas and are responsible for the release of insulin and glucagons (Guido et al., 2006). The