Aspirin Essays

acid, or Aspirin, is a widely popular over-the-counter medication2. Part of a medication class called ‘NSAID’s (non-steroid anti-inflammatory drugs), aspirin is commonly used in the treatment of simple inflammatory ailments such as headaches and low-grade fevers2. The synthesis of aspirin is relatively simple. The two reactants are acetic anhydride and salicylic acid and the products are acetylsalicylic acid and acetic acid1. One method used to analyze the purity of a synthesized aspirin product is

The chemical I will be looking at today is Aspirin. Aspirin is a medicine that was first produced 110 years ago. It came from salicylic acid found in plants such as the willow, and since then it has always been used. In 3000 BC the Egyptians used myrtle and willow to stop and reduce ones pains or fevers. In 30 AD Roman and Greek physicians discovered that the willow leaf could cure and help inflammation. There was one problem, the taste of the salicylic acid had a horrible taste causing vomiting

Acetylsalicylic acid, or commonly known as “Aspirin” is widely used as a pain reliever, anti-inflammatory agent, and an antipyretic (fever reducer). Aspirin is a considered one of the most versatile drugs known to modern medicine. Aspirin’s active component, Salicylic acid, was initially isolated by Edward Stone. He isolated salicylic acid from the barks of a willow tree and derived from willow bark extracts. Salicylic acid is not used like it used to be because of the irritable effects it has

V. Results and Discussion One of the objectives of this exercise is to synthesize acetylsalicylic acid (aspirin) from salicylic acid. The mechanism for this synthesis is through nucleophilic acyl substitution. Acetic anhydride was the acetylation reagent used with the salicylic acid. The mechanisms and the reaction involved in the synthesis are seen in the following figure. 1.00 gram of fine white salicylic acid powder was weighed in a clean, dry 125mL Erlenmeyer flask. 3mL of strong smelling

concentration of salicylic acid, using the standard solution. b) To find the concentration of aspirin at the various time intervals using the molar absorptivity value in the previous part, initial concentration of aspirin and the concentration of salicylic acid obtained from the decomposition of the aspirin pill. c) Lastly, to calculate the rate constant of the decomposition of aspirin by plotting a graph of ln[aspirin] against time and making use of the gradient of the best fitted line along with the standard

the compounds (aspirin, acetaminophen, and caffeine) were successfully isolated from the analgesic (Excedrin tablet). In figure 1, the separation of the compound in the TLC analysis correlates with the TLC analysis in figure 2. Furthermore, Rf index calculations of the TLC analysis demonstrated that the compounds (aspirin, acetaminophen, and caffeine) were separated. The Rf calculations of aspirin in table 1 shows an Rf value of .491; however, in table 2 the Rf value of aspirin was calculated to

Precautions Before Taking Mefenamic Acid Although mefenamic acid is a medication that may be bought over-the-counter, there are some things to keep in mind before taking it, including: • Tell your doctor/pharmacist if you are allergic to mefenamic acid, aspirin or other NSAID such as ibuprofen or naproxen. It is also safe practice to inform your doctor about other allergies because

Citric acid, aspirin and sodium hydrogen carbonate are the main constituents of alka seltzer. Its main role is to reduce headaches, period pains, migraines, muscular pains and symptoms of colds and flues, as well has curing problems related with an upset stomach. Aspirin works to reduce pain and swellings; it is an anti- inflammatory drug and belongs to a group of drugs called NSAIDs as it does not contain steroids. The enzyme cyclo-oxygenase which speeds up the production of prostaglandins is blocked

TLC Analysis of Analgesic Drugs Introduction The purpose of this experiment was to use thin-layer chromatography (TLC) to determine the composition of various over-the-counter analgesics (acetaminophen, aspirin, caffeine and salicylamide). The methods necessary was thin-layer chromatography Experiment Scheme Prepared at least 12 capillary micropipets to spot the plates. Then obtain two (silica) TLC plates and handle them carefully or the adsorbent may flake off. Handled them only by the edges. Used

Aspirin, Acetaminophen, an Ibuprofen have been around for centuries. They are mainly used to help the sickness of people, which may be minor or major. Acetylsalicylic Acid is another common name Aspirin maybe called. Aspirin treats minor aches, fever, and swelling. Aspirin has also been known to reduce the risk of a heart attack. Aspirins can be used in tablets, capsules, and caplets. Aspirin has also been known to be used in a powdered form. Aspirin has the chemical formula of C9H8O4. Aspirin was

Thin Layer Chromatography (TLC) Abstract This experiment uses the TLC chromatography technique to identify the presence of acetylsalicylic and Acetaminophen in analgesic drugs (Tylenol and Anacin). It was found that the Anacin and acetylsalicylic had very closer Rf values (0.8 and 0.79). The Tylenol and acetaminophen had closer Rf values (0.54 and 0.58). Hence, Acetylsalicylic acid and acetaminophen were present in Anacin and Tylenol tablets respectively. Introduction Chromatography is the technique

was first released in the UK and the USA follower in 1974. Aspirin is an analgesic drug used for minor pain, to reduce fevers, and also is also an anti-inflammatory drug. It was created in the late 1800 's. Recently many people have been using it to prevent blood clot formation. If taken in low doses aspirin can help prevent strokes and heart attacks. Today it is given to patients after they had heart attacks to prevent death. Aspirin was created over 100 years ago. However it is still one of the

ethanoic anhydride to the salicylic acid and swirled the contents, this mixes together the two chemicals. We then added 5 drops of concentrated sulphuric acid to the flask and thoroughly swirled the mixture, this creates the solution that makes the aspirin. We then warmed the flask for 20 minutes in a 400cm3 beaker of hot water which was approximately 60°C, we made sure the flask did not go above 65°C because this could have caused the contents to evaporate. Part 2: Using a 25cm3 measuring cylinder

Utilizing the techniques of acid-base extraction and Thin Layer Chromatography we were able to extract the three active components of Excedrin and confirm the identity of each compound. The three active components of Excedrin- aspirin, acetaminophen, and caffeine- all have varying acidities and polarity which allowed for the successful usage of acid-base extraction and TLC respectively. Acid-base extraction was applied by adding our compound to a basic solvent in order to isolate the components by

5.1 MATERIAL USED Azathioprine was obtained as a gift sample from M/s Psycorem Pharmaceuticals Ltd. (Ludhiana, India); Carbopol 934 was purchased from Sunchem (India), Tween 20 and Span 20, Methyl and Propyl paraben, Light liquid paraffin, Propylene glycol, Triethanolamine (TEA), and Ethyl alcohol were purchased from M/s Central Drug House Pvt. Ltd ( New Delhi, India). Doubled distilled water was used throughout the study. 5.2 METHOD OF PREPARATION OF AZATHIOPRINE EMULGEL 5.2.1 Preparation of Emulsion

ABSTRACT: Pantoprazole sodium is an antiulcer drug. This compound inhibits gastric acid formation and thereby it is very efficient for the treatment of gastric and duodenum ulcers. But pantoprazole sodium is acid labile drug that will degrade in acidic environment of stomach resulting in therapeutic inefficacy. Hence it is necessary to bypass the acidic pH of the stomach which can be achieved by formulating delayed release dosage forms (single unit or multiple units) by using different enteric polymers

The overall aim of our experiment was accomplished due to the fact that the compound produced was tested to be pure paracetamol. Its purity was tested by TLC, melting point range and NMR analysis. For the Melting Point Range Determination, samples of our re-crystallised p-aminophenol and paracetamol were placed into capillaries and into the melting point apparatus where data was recorded during the melt. Then, for the Thin Layer Chromatography, a TLC plate was prepared with four small dots loaded

Thin Layer Chromatography Lab Report Miranda Tyree Lab Partner: Caitlin Price TA: Yi Zhou Lab Time: Thursday, 12 pm Lab Room: 207 Date: 09/23/2016 Abstract Experiments were performed to determine the active chemical ingredients in Tylenol and Anacin. The active chemical ingredients were determined by performing thin layer chromatography of four substances: Tylenol, Anacin, acetaminophen, and acetylsalicylic acid. The identity of the ingredients was then confirmed by using the co-spotting thin

the edge of the silica TLC paper and divided into five parts with a ruler and a graphite pencil. One of the prepped silica TLC was used as the Reference Plate and the second as the Unknowns plate. The reference plate was spotted with Acetaminophen, Aspirin, Caffeine, Safinamide, and the standard reference mixture. The Unknowns plate was spotted with solutions identified as solution 1 through 4 and the last spot was spotted with the standard reference mixture. The micropipettes were used for spotting

Aim This experiment separates the constituents of a commercial headache powder employing the use of extraction method. The active ingredients of the commercial headache powder were extracted by dissolving the powdered tablet in propanone solvent. The suspended fine particle binders in the propanone solution were removed by filtration method. The solid analgesia was obtained by evaporating propanone solvent. It was then collected on Hirsh funnel by filtration. Melting point determination was performed