Clinical pharmacology Essays

EXENATIDE Pharmacology Exenatide is a synthetic form of naturally occurring peptide Exendin-4 in Gila monster 16. It has 50% of sequence homology with native GLP-1 with the substitution of amino acid Arg with Gly at 2nd position, which provides resistance against DPP-4 and a half life of ~2-4hr. It is administered 60min before breakfast and dinner, with a predominant effect of reduction in PPG (Postprandial glucose) 17. Exenatide is rapidly absorbed following subcutaneous administration and eliminated

gene therapy, but rather than altering genes to treat or prevent an illness, they are changed to make normal gene perform differently (McGrath, Cowan, 2008). -Gene doping can be utilized to restoring muscle lost to age or disease and has enter the clinical market (Gordon, Jonathan, & James, 2007) -It can be used to denote strategies in which genes or genetic elements are introduced into cells from outside, to remedy inherited or acquired genetic disorders (Hassan, Mai, & Robert, 2005). Cons of gene

specialist's supervision. A Physician Assistant can diagnose a patient and recommend treatment. Physician assistant online course incorporate a mixture of address courses in wellbeing related ranges, in addition to hands-on research center direction and clinical turns. These course permit contender to have practical experience in territories, for example, inner drug, crisis solution, or neonatology. The responsibility of the Physician assistant requests insight, sound judgment, savvy trustworthiness, suitable

There have been numerous studies such as multiple systematic review of clinical trials and systematic reviews of the systematic reviews. One of such review is Ernest’s “A systematic review of systematic review of homeopathy” published in the British Journal of Clinical Pharmacology. This systematic review concluded that the existing evidence does not support claims that homeopathy is anything more than a mere placebo. Similarly

My career I chose is pharmacy technician. I think I would like to become a pharmacy tech because I like to be one on one with someone. Another reason I would like to become one is because I could work in any pharmacy. Being a pharmacy technician would allow me to have a flexible schedule. It would also be good I the future because later I could go back and get a degree in pharmacy. A pharmacy technician would help licensed pharmacists dispense prescriptions medication to customers or health professionals

credentialed to write prescriptions for selected medications (Benson, Schreck, Underwood, & Greathouse, 1995, p. 381). Hence, I would consider attending annual trainings and competency checks to build up my confidence. However, for now, this course on pharmacology is of great value in building up my foundational knowledge and skills in preparation for what the future may hold for our profession in the field of drug

D’aquino, Peter. “The Brave New World of Chinese Herbal Medicine.” Oriental Medicine 2014: 8+. CINAHL Complete. Web. 9 Feb 2016. The author, a licensed acupuncturist, discusses the history, legacy, and the possible future of Chinese Herbal Medicine in this journal article. He begins by identifying the prevalent reputation that herbs possess. Although this ingredient has been utilized safely and commonly in Chinese history, adverse effects can surface if taken incorrectly. Regardless, TCM has had

decisions inside the pharmacy setting. Within this role, I am undertaking a Pharmacy Advisor Programme supplied by Boots and accredited by the GPhC. This programme encompasses both dispensing and healthcare knowledge that will aid me greatly with the clinical aspects of the degree, as well as my professional development. As such, I believe these experiences evidence knowledge and skills that are highly beneficial for the course. It provides me with an excellent knowledge base to support my future ambitions

The five dimensions include disease, medication, demographic and socioeconomic factors, patient and close relatives, and health care system. For an example, if the patient lack of symptoms, it will lead them to non-adherence to the pharmacology therapy. When the prescription is very complex, it also will lead to this issue especially older patients who having difficulty in remembering the drug to be taken. Sometimes, when the patient experienced any side effect after taking the therapy

Analyzing a Current Health Care Problem or Issue This essay examines medication errors’ sources, effects, and prevention measures. This paper seeks to raise awareness and knowledge of this critical patient safety issue by exploring the definition, key players, and root causes of medication errors. The information presented will help identify the elements, solutions, and implementation to reduce medication errors, increase medication administration procedures, and improve patient safety in healthcare

magnesium alumina meta silicate, low substituted hydroxylpropyl cellulose and film coating containing the following inactive ingredients: titanium dioxide, hypromellose, colloidal anhydrous silica and triethyl citrate. 2.2 Mechanism of Action and Pharmacology: Pitavastatin drug competitively inhibits HMG-CoA reductase enzyme, which is a rate-determining enzymeinvolved in the biosynthesis of cholesterol, in the manner of competition with a substrate sothat it inhibits cholesterol synthesis process in

3.Pharmacology 3.1.Mechanism of action Febuxostat is a non purine compound and selective inhibitor of xanthine oxidase that has been developed for the treatment of hyperurecemia and gout. It has been found to have inhibitory activity for xanthine oxidase(XO)/xanthine dehydrogenase(XDH) during evaluation of a range of newly synthesized molecules. In humans, the xanthine oxidoreductase enzyme(XOR) catalyzes the last 2 steps in uric acid synthesis,the oxidation of hypoxanthine to xanthine and xanthine

Elderly patients often experience multiple co-morbidities and prescribed number of medications thereby increases the risk of adverse events (AEs), drug-disease and drug-drug interaction. This risk is more by age-related physiological changes, which influence ADME and pharmacodynamics. Particular drugs shows additional risks to elderly patients as a result of these changes, e.g. increased risk of upper GIT bleeding with NSAIDs and increased risk of falls and prolonged sedation with long-acting benzodiazepines

Pharmacology: Celebrex Yiu Wing Man, Vanessa (13000332) Celebrex: A powerful painkiller Osteoarthritis is a chronic condition where breaking down the cartilage,causing stiffness, pain and loss of the joint movement. Celebrex (Celecoxib) is non-steroidal anti-inflammatory drug (NSAID) which is prescribed to treat inflammation and pain. It is most typically used for treatment of acute pain and osteoarthritis to relief the symptoms and signs. People chose Celebrex rather than others for the same purpose

I chose Pharmacy Tech because my life involves around medication and my family. So as I was growing up, I always helped my family which are my number 1 priority. When I was in first grade at the age of six years old, I tend to get sick a lot of times. So when I did get sick my aunt will go buy me some OTC children’s ibuprofen for my fever’s, then I will read the directions on how to take it, and read the package insert that involves the warning on what not to take with the medication, and side effects

named as botanical medicine, medical herbalism, herbal medicine, herbology, herblore and phytotherapy. The scope of herbal medicine is sometimes extended to comprises fungal and bee products, as well as minerals, shells and certain animal parts. Pharmacology is study of medicines that obtained from natural sources. The plants are the lushest source for drugs traditional systems of medicine, modern medicines, nutraceuticals, food supplement, folk medicines, pharmaceuticals intermediates and chemical

Designing a Therapeutic Dosing Regimen for a Novel Potential Treatment of Alzheimer’s Disease Allopregnanolone is a metabolite of progesterone and a naturally occurring steroid hormone, which acts as a positive allosteric modulator on the GABAA receptor, producing anaesthetic, anxiolytic and sedative effects. The notable exception to this appears to be in the brains of adolescents, where it acts as a GABAA antagonist, causing mood swings. (National Center for Biotechnology Information, n.d.) It

INTRODUCTION: Gemfibrozil[1-3], 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid (Fig.1), is a fibric acid anti-lipemic agent used to treat hyperlipoproteinemia and as a second-line therapy for type IIb hypercholesterolemia. It acts to reduce triglyceride levels, reduce VLDL levels, reduce LDL levels (moderately), and increase HDL levels (moderately).it increases the activity of extrahepatic lipoprotein lipase (LL), thereby increasing lipoprotein triglyceride lipolysis. It does so by activating

In clinical trials, efficacy and safety are measured by means of certain predetermined endpoints, or outcomes. The main objective of a Phase 3 trial is to demonstrate the efficacy of a drug in the actual target population that is proven in a statistically and clinically significant manner. A Phase 3 trial has a clearly defined primary endpoint(s), pre-specified even before study initiation, because they will determine the power of the study and ensure that the research question is specific. Clinical

specific labeling for children. The Food and Drug Administration (FDA) requires that drugs be tested for safety and efficacy in a specific population, at a specific dosage, and for a specific time period before a drug is FDA approved for clinical use. Most clinical research for FDA approval protocol excludes children. Children are more vulnerable to adverse drug reactions and therefore