FIG : NORMAL HEART FIG : HYPERTROPHIC HEART
(Hypertrophic cardiomyopathy,Cleveland clinic)
Above figure in the left shows physiology of the normal heart while the right one shows physiology of hypertrophic heart having leaky mitral valve, thickened septum and narrowed outflow tract.
Symptoms of hypertrophic cardiomyopathy: (Marian Ali .,2010)
• Arrhythmias: This condition mainly occurs when heart rhythms of the patient are irregular due to improper flow of blood from the heart to rest of the body. This could further lead to cardiac failure along with sudden death of the patient.
• Syncope: It does not occur frequently but usually in patients having left ventricular outflow
…show more content…
When both left ventricular hypertrophy and right atrial enlargement is present, this a strong indication of HCM.
• Left axis deviation
• Deeply inverted T waves
(Gersh BJ, et al. 2011) Fig : ECG of Left ventricular hypertrophy Fig : ECG of normal heart.
( uptodate, 2014)
The above ECG figure in left shows ST-T wave abnormalities which is the indication of left ventricular hypertrophy where as the ECG figure in the right shows the normal echocardiogram having normal sinus rhythm at a rate of 75 beats/min, PR interval of 0.14 sec, a QRS interval of 0.10 sec, and a QRS axis of approx. 75°.
Echocardiography
Generally there are two types of echocardiography is performed for hypertrophic cardiomyopathy
Transthoracic echocardiogram: transducer is placed over the chest to aim the ultrasound beam to heart ( HCM, MAYO CLINIC)
Transesophageal echocardiogram: transducer is to the throat with the help of flexible tube and ultrasound is produced. This is rarely done, performed only if it is difficult to get clear image of heart by standard echocardiogram (HCM, MAYO CLINIC) Fig : echocardiogram showing HCM
(Maron BJ, et al,
…show more content…
III. Familial and senile amyloid heart disease : familial amyloid heart disease is inherited and is caused due to overproduction of protein transthyretin ,which is produced in the liver while senile amyloid heart disease is caused due to deposits of normal protein transthyretin in heart tissues (Cleveland clinic.,2014).
B ) HEMOCHROMATOSIS :
It is also known as bronze diabetes occurs when exceesive loads of iron get deposited in sarcoplasmic reticulum of organs. This can lead to excessive fibrosis and cell death and may also result in dilated or restrictive cardioyopathy (Sisakian H.,2014).
C ) SARCOIDOSIS : It is a disease resulting in granulomas formation in myocardium that cause restrictive cardiomyopathy and mostly leads to dilated cardiomyopathy ,also it can be found in patients with splenomegaly, skin rashes or having cardiomyopathy (Cleveland clinic.,2014).
Diagnosis of restrictive cardiomyopathy
It is one of the rarest cardiomyopathy. It is difficult to diagnose in the early stage due to lack of symptoms. Diagnosis of restrictive cardiomyopathy is based on the
1. Examination of patient
2. Test.
Physical exam: A physical may show
• Enlarged or bulging neck veins
• Enlarged
Pathophysiology When Pulmonary Stenosis is present, resistant to blood flow cause right ventricular hypertrophy – right atrial pressure will increase – reopening of the foramen ovale, shunting of unoxygenated blood into the left atrium, systemic circulation. Clinical manifestation: Cyanosis, characteristic murmur , cardiomegaly . Treatment: Baloon angioplasty (neonate).
Pulmonary: Chest wall symmetric, respirations even and unlabored. Lungs CTA. Cardiac: Sinus tachycardia, NL S1, S2. No murmurs or rubs.
Normally blood entering the right side of the heart stays on the right side (this is low-oxygen blood), and blood on the left side of the heart stays on the left side (this is oxygen-rich blood) which is then pumped to the rest of the body. But in this particular condition when a defect or "hole" is present between the ventricles (or lower chambers), blood from the left side of the heart is forced through the defect to the right side every time the heart beats. It then goes back to the lungs even though it is already rich in oxygen. Because of this, blood that is not yet oxygen-rich can 't get to the lungs. The most common signs and symptoms are trouble eating and gaining weight, breathlessness and easy fatigability in
Damaged heart valves, toxic exposure, such as alcohol, prolonged arrhythmias, and infections are all other causes
This can lead to heart and damage the heart muscle permanently crisis; • high blood pressure, which is also called hypertension; • disease of the heart valves - there may be a leak in the valves or those may stiffen, especially the sigmoid valves and mitral; • a disorder of cardiac muscle, which is also called cardiomyopathy. That may be caused by a virus, bacterium or other infections; • damage to the heart caused by the abuse of alcohol or drugs; • congenital heart disease and heart defects that exist at birth; • an irregular heartbeat, especially if there is rapid or chaotic. The heart does not pump enough blood when his rhythm is abnormal; • certain lung disorders, such as pulmonary hypertension, which occurs when the right ventricle dilates, causing heart failure on the right. Normal Heart congestive heart é START T How is the diagnosis?
Firstly, the formation of the valve must be correct, and it must be flexible enough to undergo the movements required of the it to ensure efficient function. Secondly, the valve must be able to open up to a certain diameter to allow the correct volume of blood to pass through into the left ventricle. Finally, the valve must be able to close firmly, in order to prevent any blood leaking back into the left atrium7. The competence of the mitral valve is essential to the efficient functioning of the cardiovascular system, and when one of the above criteria for an efficiently functioning valve is not met there are several conditions that can develop, which can and do cause many problems for those who suffer from them. The most common problems include mitral valve regurgitation, mitral valve stenosis and mitral valve
The other being dextrocardia situs inversus (its further divided). There is no know causes to lead up to have dextrocardia. You many have defects in the heart chambers and/or valves. Your heart may develop differently because of anatomical problems such as problems in your lungs, abdomen, or chest that can cause them to shift differently. You may have more problems with other vital organs.
Because of this inability to contract effectively, the rest of the vital organs receive inadequate amount of blood resulting to inadequate tissue perfusion. There are two types of left-sided HF; systolic and diastolic failure. Systolic failure happens when the left ventricle doesn’t have the enough energy to pump normally the blood to the general circulation. As for diastolic failure, the left ventricle loses the ability to fill itself with blood during resting period resulting to inadequate amount of blood to be pumped out to the circulation (Weinrauch, 2008). The diastolic dysfunction will eventually lead to right-sided heart failure.
Bradycardia is when the heart beat is slower than normal 21. Cardioplegia is a procedure that is used to stop the heart activity for a short period of time. This type of procedure is used for heart surgeries. 22. Cardiomyopathy is heart muscle disease that causes the muscle to become enlarged and stiff.
Hypertrophic Cardiomyopathy (HCM) “is a genetic condition, its main characteristic is thickening (hypertrophy) of the heart muscle.” It is estimated that in recent study that student athletes have nearly a four times higher rate of cardiac arrest than their peers (p.3). “Hypertrophic Cardiomyopathy usually comes from a
Heart Failure (HF) occurs when the heart is unable to pump the necessary volume of blood to meet demands of tissue metabolism. This condition can be acute; it may have a fast onset or clinical change of signs and symptoms (Andrietta, Moreira, & Barros, 2011). The patient with heart failure presents with shortness of breath, cough, or difficulty breathing on activity. The patient often experiences acute exacerbation of symptoms resulting in hospitalization for medical management. Congestive Heart Failure (CHF) continues to be a major public health problem associated with high morbidity and mortality.
Electrocardiograms are abnormal in 75-90% of patients with HCM with abnormalities such as ST changes with T wave inversions, and prominent Q waves especially in the inferior and mid-precordial leads. 22, 23 Non-invasive imaging is important for diagnosis, including echocardiogram and MRI.20 Coronary artery anomalies The second most common cause of SCD are coronary abnormalities with ectopic origins from aorta (also known as anomalous origin of a coronary artery (AOCA) from the opposite sinus of Valsalva) and the pulmonary trunk (also known as anomalous origin of a coronary artery (ALCAPA) from the pulmonary artery) most commonly.24 In cases of AOCA that cause SCD, the left or right coronary exits from
Further improvements in its sensitivity, and size were made, and adapted from the field of Obstetrics and Gynecology to Cardiology, to be used in echocardiography. Such a development allowed for improved methods of understanding the heart condition of patients and allowed the quality of cardiac healthcare to be increased since aliments of the heart might be determined without resorting to surgery or using harmful chemicals, even though it is in low
Kent, M., 2013. Advanced biology, 2nd ed. Laizzo, P., 2016. HANDBOOK OF CARDIAC ANATOMY, PHYSIOLOGY, AND DEVICES. SPRINGER, S.l.
The heart is a muscular organ that pumps blood throughout the body. The human heart is con shaped and has the size of a closed fist. In accordance to that, a bigger person has a bigger fist and therefore a bigger heart. Moreover, it is the only involuntary striated muscle that is consisting of four chambers: two upper chambers “atria” and two lower one “ventricles”, where the right side of the heart is separated from the left side by an inter-ventricular septum, and they are connected by pulmonary arteries and pulmonary veins.