Myeloproliferative Neoplasms “Myeloproliferative Neoplasms (MPN) are group of diseases that cause the bone marrow to create too many red blood cells, white blood cells, or platelets.” Normally, the bone marrow would make immature blood cells, or blood stem cells, that would develop into a myeloid or lymphoid stem cell. The lymphoid cell would develop into a white blood cell, and the myeloid cell would develop into either a red blood cell, platelet, or a white blood cell. The white blood cells fight disease and infection, the platelets clot the blood, and the red blood cells carry oxygen throughout the body. Dysfunction of these cells is caused by the overdevelopment of one of the others.
There are six main types of chronic Myeloproliferative …show more content…
This disease is characterized by the overproduction of immature white blood cells, known as granulocytes, in the bone marrow. This disease rarely occurs in children, it usually affects middle aged individuals. As in most other Myeloproliferative Neoplasms, this is a result of the body telling the blood stem cells to keep developing into a specific blood cell, in this case they are the granulocytes. This is abnormal and eventually these granulocytes will over crowd the red blood cells and the platelets in the bone marrow, not allowing room or healthy development of other white blood cells, red blood cells, and platelets. This may cause anemia or infection. Other symptoms of CML are feeling very tired or losing weight for no known reason. However, sometimes CML does not cause any of these symptoms. The chance of recovery of CML depends on the patient’s age, the quantity of blasts, or immature cells, in the blood or bone marrow, the size of the patient’s spleen at the time of their diagnosis, and their overall …show more content…
These include a physical examination and history, a complete blood count (CBC) with differential, peripheral blood smear, blood chemistry studies, a bone marrow aspiration and biopsy, cytogenetic analysis, and a JAK2 gene mutation test. The three that are most likely to be used are the physical, the complete blood count, and the biopsy. A physical examination and history is simply an examination of the body, evaluating an individual’s overall signs of health in search of anything abnormal. This will also involve asking about the patient’s past health habits and illnesses. A complete blood count is a procedure in which the patient’s blood will be drawn and evaluated for the amount of hemoglobin (protein that carries oxygen) in the blood, the quantity of the red blood cells, white blood cells, and platelets in the blood, and how much of the blood sample is composed of red blood cells. A peripheral blood smear may also be used if blood is drawn because it checks the blood for things like an irregular teardrop shape of red blood cells, the amount and different kinds of white blood cells and the amount of platelets. It also determines whether or not blast cells are present. In a bone marrow aspiration and biopsy, blood, bone marrow, and bone is removed by a needle, called a Jamshidi needle, inserted into the hip or breast bone. It is then observed by a patholigst through a
The Process of Drawing Blood As a Phlebotomist there is a process that must be followed when drawing blood. The first step, Make sure you always identify the patient, Check the paperwork to see what test needs to be performed; therefore, you will know what color collection tubes are required. Next, wash your hands, prepare the work station, and set up all the equipment that is necessary to perform the process. Then, apply gloves to ensure safety precautions for you and the patient.
Ever since we are little, most of us hate the idea of needle pricks at the doctor’s office. We cringe, cry, hold our moms hand or even embarrassingly pass out. Although we are difficult patients during the collection of blood specimens, it is actually crucially important for a Phlebotomist to perform a proper collection of specimens. Phlebotomy can be the backbone of the laboratory and provide proper diagnosis for patients. Improper collection can lead to complications, including misdiagnosis.
Hyperviscosity syndrome results from increased serum viscosity due to high protein content in multiple myeloma. Clinical pearls: • Multiple Myeloma is a plasma cell malignancy that causes end organ damage- CRAB Calcium elevated Renal failure Anemia Bone lesions • Median age of diagnosis is 70 years
Christina George #109193966 HAN 312 FALL 2015 CASE STUDY PROJECT PART 1 This assignment is due Friday 10/23/2015 by 9 am 1. 5 POINTS: Briefly explain the disease or disorder you picked in no less than five but no more than 10 sentences • Systemic lupus erythematosus (SLE) is a chronic autoimmune disorder that can affect any organ in the body. Symptoms range from mild to severe.
Specialists aren’t completely sure on what causes non-Hodgkin’s, lymphoma, but they do know “occurs when your body produces too many abnormal lymphocytes- a type of white blood cell”(Non-Hodgkin’s Lymphoma-Mayo Clinic). Non-Hodgkin’s Lymphoma can begin in two different locations, it can begin your T-Cells or in your
Lymphoma comprises a histologically heterogeneous group of cancers arise from the cells of the immune system with enlargement and propagation of lymph nodes or secondary lymphoid tissues.(1). " About 54 percent of the blood cancers that occur each year are types of lymphomas", The main types of lymphomas are Hodgkin lymphoma and non-Hodgkin lymphoma. non-Hodgkin lymphoma is a cancer that starts in cells called lymphocytes , which are part of the body’s immune system. There is different signs and symptoms can caused Non-Hodgkin lymphoma , it depending on where it is in the body for example: Fever, Weight loss, Night sweats, extreme tiredness ,anemia , Enlarged lymph nodes, Swollen abdomen (belly), Feeling full after only a small amount
Sickle cell anemia is a genetic disorder it is also known as sickle cell disease. A genetic disorder is something that is passed down from parent to child. This is a disease of the hemoglobin. Hemoglobin is a red protein responsible for transporting oxygen in the blood of vertebrates. Sickle cell anemia causes your red blood cells to stiffen, although your red blood cell are supposed to be flexible.
Pathophysiology “ Multiple sclerosis cam be defined as an autoimmune disease that affects the myelin sheath and conduction of pathway of the nervous system (CNS). It is one of the leading causes of neurologic disabilities in young adults. It is a chronic disease that is characterized by periods of remission and exacerbation.” (Ignataviscius & Workman, 2013, p. 978) Multiple sclerosis affects all patient’s differently, progressing at different rates over different periods of time.
What are the primary pieces of evidence from the CBC that point to this diagnosis? Anemia is a condition that develops when a person’s blood lacks enough healthy RBC or hemoglobin. The effect is an insufficient amount of oxygen to the tissues. In Harold’s case, the main parts of evidence from the CBC include the low RBC, hemoglobin, and hematocrit.
Towards the end of the procedure the nurse counted all sponges and needles with the scrub to make sure that no equipment was left within the patient. The nurse also continued to document information such as the length of the surgery and the amount of blood lost throughout the procedure. Lastly, the circulating nurse cleaned the room and then transferred the patient into a hospital bed to be transferred to the post-anesthesia care unit. Ignatavicius and workman (2013) addressed that these are all responsibilities of the circulating nurse (p.
So, it is like a giant blood blister?" Or better yet, "What if your hand never stops swelling one day and it swells so big that it just explodes? " This was what it was like most of my life going to school with my condition. Until one day mom got a call from our specialist that