Nt1310 Unit 3 Lab Report

Activity 1
Increasing extracellular K+ reduces the net diffusion of K+ out of the neuron through the K+ leak channels because it caused to decrease in the concentration gradient.

Increasing extracellular K+ causes the membrane potential to change to a less negative value because extracellular K+ is increasing, which it will cause intracellular K+ to be less.

A change in extracellular Na+ did not alter the membrane potential in the resting neuron because there are a lot of K+ leak channels than Na+ leak channels

The relative permeability of the membrane to Na+ and K+ in a resting neuron is that Na+ leak channel is less, but K+ leak channels has more so the membrane become less permeable to Na+.

A change in Na+ or K+ conductance would affect the resting membrane potential by changing the difference

The effect of lidocaine differ from the effect of TTX is lidocaine’s effect is reversible and TTX’s effect is inreversible.

The response at R2 after lidocaine application necessarily wouldn’t be zero because of the action potential. Some axons may be unaffected that cause a response to be greater than zero.

Fewer action potentials are recorded at R2 when TTX is applied between R1 and R2 because TTX blocked the voltage gated channels in R2. Fewer action potentials recorded at R2 when lidocaine is applied between R1 and R2 because it blocked membrane potential and lidocaine’s effect is reversible.

A dentist should inject the lidocaine to block pain perception in the nerve so it can prevent pain on the area. TXX is not used because it is irreversibly blocked it.

Actity 5
Inactivation is voltage-gated sodium channel refuse sodium to pass through.

The absolute refractory period is an action potential can’t be triggered in refractory period, even a greater stimulus is applied.

The threshold for the second action potential change as you further decreased the interval between the stimuli is