Doxorubicin Essays

Drug profile of doxorubicin Doxorubicin (DOX) also known as Adriamycin is categorized as anthracycline antiobiotic. It was first extracted from Streptomyces peucetius var. caesius by aerobic fermentation followed by solvent extraction and purification by chromatography in 1970s. It is also extracted from Streptomyces coeruleorubidus or chemically synthesized from daunomycin (its natural analog). DOX differes from daunorubicin only by a single OH group (Arcamone et al., 1972). DOX is a broad spectrum

Answers for: Part I 1- There are two types of twins: • Monozygotic twins, also called “Identical twins:” They arise from a single sperm and single egg. Then the zygote is divided into two identical zygotes that carry the same genetic material and the same physical appearance. • Dizygotic twins: also called “Non-identical twins:” They arise from two sperms and two separate eggs. Thus, the two zygotes will not carry the same genetic materials or the same physical appearance. 2- Identical twins

macrophage-mediating cytotoxicity. MTT assay is a highly sensitive and reproductive method, it doesn’t require presence of radioactive compounds, easy to perform and quantify and it’s a rapid method.(Ferrari et al., 1990) A study was conducted on doxorubicin (DOX) and doxorubicin poly(N-isopropylacylamide-co-acrylic aid) (PNA) conjugates to assess their cytotoxicity

For some cancers, chemotherapy alone can destroy all the cancer cells and cure the cancer (primary treatment). As an adjuvant treatment, chemotherapy is given prior to, or after other methods, to increase the effectiveness of cancer treatment. Most often, adjuvant chemotherapy is given after other therapies have destroyed the clinically detectable cancer cells. The purpose of adjuvant chemotherapy is to reduce the risk of recurrence or to prolong survival. If cure is not possible, chemotherapy may

vincristine, procarbazine, and prednisone. ADVB, which is Adriamycin, bleomycin, and vinblastine and dacarbazine are also medications for treatment of the disease. Stanford V includes doxorubicin, vinblastine, mustard, bleomycin, vincristine, etoposide, and prednisone. BEACOPP include bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone. These sources of treatment are all given intravenously except prednisone and

Different types of treatment options are available for patients with bladder cancer. There are four types of standard treatment used, which include surgery, radiation, chemotherapy and biologic therapy. Doctor’s recommendation on which treatment is determined by which stage the patient is at. There are also clinical trials in the process, which is a research study that helps improve the current standard treatments. The first standard treatment option is surgery. There are four types of surgery

Common drug combanations for lung cancer are: Cyclophosphamide, doxorubicin and vincristine ("Chemotherapy," n.d.). Chemo can be used together with other treatments for different goals: Neo-adjuvant is used to make tumor smaller before surgery or radiation therapy. Adjuvant chemotherapy is used to destroy any remaining

• Patient Information: -Name/Gender/Race: Valentina Palmero/Female/Caucasian -DOB: 12/4/1992 -Age: 24 years -Date of exam: 4/12/17 • Chief Complaint: Night sweats and unexplained weight loss. Patient says she has recurring episodes of extreme perspiration, soaking her clothes and bedding during sleep. Patient also notes that she has been losing weight for no apparent reason, dropping 10 pounds in a month. • History of Present Illness: The patient is a 24 year old female complaining of night sweats

Introduction : Liposomes were discovered in the early 1960 by Bangham and colleagues (Bangham et al., 1965 ) and subsequently became the most extensively explored drug delivery system. Liposomes are concentric bilayered vesicle in which an aqueous volume is entirely enclosed by a membranous lipid bilayer mainly composed of natural or synthetic phospholipids. A liposome can be formed at a variety of sizes as uni-lamellar or multi-lamellar construction, and its name relates

The problem with these MOFs was they were made of chromium, which was considered to be toxic to be used as a drug delivery vehicle. So another alternative was suggested, Fe-MIL-100 has been developed as a biocompatible drug carrier104.Trimesic acid (BTC or 1,3,5 benzene-tricarboxylic acid) is the organic linker. This cubic mesoporous iron(III)trimesate MIL-100(Fe)105 exhibit a low toxicity character106 raise exceptional interest as drug delivery and bio imaging systems 107. Apart from Cr and Fe,

JENNY COSTE This is the case of Jenny Coste, 10 years old and was diagnosed with Acute Lymphoblastic Leukemia. She felt a sudden pain in her legs, was feeling sick and has shortness of breath. She undergoes intensive chemotherapy and have been in and out of the hospital for 18 months. She had a remission for a fleeting period, but unfortunately a relapse occurred. Her health being swiftly dropped despite assertive effort of treatment until her family decided to put her in palliative care. Acute

Since the development of the germ theory, many scientists, working with plant and animal infecting microbes, have focused their research efforts on the microbes that cause disease (Ainsworth, 1981). Endophytes (fungi and/or bacteria that live within the tissues of plants) largely appear to be the inverse of plant pathogens since generally they represent cryptic benign infections of healthy plants. The term endophyte (Gr. endon, within; phyton, plant) was first coined by De Bary (De Bary, 1866) and

Chemotherapy most commonly known as “chemo” is a long and lengthy procedure used to destroy cancer cells, control its growth and spread, or provide ease and comfort to the patient. Chemotherapy treatment began in the 1940’s with nitrogen mustard which later on developed in to aminopterin. Chemotherapy comes with many side effects and risks; it not only affects the patients mind but also their body. Even though chemotherapy has its risks it is still considered to be an effective treatment option

SITE SPECIFIC DRUG DELIVERY Site specific delivery systems are unique forms of delivery systems whereby the drug or medicine is specifically or selectively delivered to a particular site in the body where it is going to exert it's action and it is not delivered to other non-target organs and cells. The main aim of site specific delivery of drugs is to develop drug concentration that is sufficient to produce therapeutic effect at the site of the disease with minimal effect to the rest of the organs

Name: Fahimeh Maghsoodi Intended Major: Pharmaceutical Sciences Degree sought: PhD STATEMENT OF PURPOSE About me and choosing North Dakota State University Firstly, I do appreciate for providing an opportunity to state my purpose. I am highly motivated Ph.D. candidate, named Fahimeh Maghsoodi who graduated with Master of Nanotechnology from Nanoscience and Nanotechnology Institute of the University of Kashan where is the polar center of Nanotechnology in my country. It is my unshakable belief

Legalization of Marijuana Drugs are everywhere, from the caffeine in energy drinks to the Tylenol taken for minor headaches; they have become a huge part of today’s world. Drugs come in a plethora of forms and have thousands of uses. Drugs are substances that alter bodily functions. They can wake up a person, put them to sleep, cause hallucinations, the list goes on. A large group of drugs today in America are pharmaceutical drugs. Pharmaceutical drugs are substances that are used for medical

MULTIPLE MYELOMA 72 year old african american male presents to your office with persistent pain in his left upper arm over the last few weeks. Pain is non-radiating and worse at night. You have seen this patient four weeks ago for the same complaint and prescribed acetaminophen. He also states that he feels exhausted lately. The patient denies any history of fever, weight loss, weight bearing or trauma. Past medical history is significant for hypertension for which he takes losartan along with a

This essay considers the impact of chemotherapy-induced alopecia (CIA) on ovarian cancer patient and the significant others and, the rationale for selecting it. It discusses on how the patient experience could be improved together with the professional and ethical dimension of practice. It is important to understand the feeling of a cancer patient experiencing CIA and its impact on the patient and significant others. Every cancer patient knows that chemotherapy is a cancer treatment with beneficial

Chemotherapy: Treatment with Side Effects Jeremy David Gunawan Bio Medicine INDONESIA INTERNATIONAL INSTITUTE FOR LIFE SCIENCES JAKARTA 2014 Abstract Chemotherapy is a primary treatment for cancer. Even though it is a treatment, chemotherapy gives a lot of side effects. Many people have zero knowledge on chemotherapy side effects and do not know what these effects can affect their life. Each drug in chemotherapy can have more than one side effect from common, less common, to rare effects

America, it was evident that high blood levels of beta-carotene could protect the body against lung cancer, melanoma and bladder cancer. This study was performed at John Hopkins School of Hygiene and Public Health in Baltimore. The above studies show similar results pointing to the fact that people with high intakes of beta-carotene have a reduced risk of cancer and heart disease. The reason? Beta-carotene stimulates a molecule that helps the immune system destroy cancer cells. It increases the