Lipid disorders Essays

INTRODUCTION Lipidoses can be defined as inherited metabolic disorders where lipids accumulate in cells and tissues; sphingolipidoses are autosomal recessive inherited metabolic disorders in which the lipid that accumulates is a sphingolipid.(1) Sphingolipids are any member of a class of lipids that contain sphingosine, an organic aliphatic amino acid, or substances that are structurally similar to sphingosine. (2). The main sphingolipids discussed will be gangliosides, globosides, ceramides and

REGULATION OF FATTY ACID METABOLISM Introduction: Fatty acids are produced by acetyl-CoA by its transformation to malonyl-COA by various known as fatty acid synthases and this takes place in cytoplasm.Acetyl-COA is fuether transformed into various fats molecules taken from carbohydrates through a process known as glycolytic pathway.This pathway basically requires glycerol along with three fatty acid molecules to form a structure called as neutral fats or triglycerols.Two fatty acid molecules basically

• Iodine Solution Weigh 7.7g of potassium iodide into a 50cm3 beaker. Use distilled water to help the iodide dissolve. Swirl for a few minutes until the iodide has completely dissolved. Using a funnel to help, pour the potassium iodide into a 500cm3 volumetric flask, make sure all traces of the solution is in the volumetric flask. Using distilled water would be a good method in order to rinse the beaker. Make the solution up to the 500cm3 mark with iodine (1% concentration) • Starch Indicator Solution

Lipid Readings & Assignment This lab consists of three parts that totals 50 points. Students should save this lab assignment to their desktop in a word document. The file then needs to be uploaded into Canvas by the due date after all questions are answered. Part 1: Cholesterol Background Information: Use your textbook, lecture notes, slide presentation and the link provided to answer the questions below. Click on the following link to access additional information on cholesterol. http://www

Lipids are an essential macromolecule found within the body and it has many structures and has a number of functions within the body. Cholesterol is a type of lipid, which is responsible for the structure of the plasma membrane in the cell. They provide a barrier between the cell and the cell’s external environment (Alberts, 2004). Cholesterol is moved around the body through two mechanisms: Low-density lipoproteins and high-density lipoproteins. High levels of LDH can cause cardiovascular disease

Introduction: Benzopinacol can be prepared from benzophenone in presence of sun light (photochemically) using isopropanol as the reducing agent in presence of acetic acid. Acetic acid is added to prevent the cleavage of benzopinacol to benzophenone and benzhydrol by the alkali derived from the glass container used for the reaction. Benzopinacol obtained in the first experiment is converted to benzopinacolone by heating under reflux (5 minutes) with glacial acetic acid containing trace amount of iodine

Lipid A Lipid A is a component of a poison responsible for the “anchoring” of the toxin to the outer membrane of immune system cells. The poison reacts with the body's immune system, causing septic shock. It is found in endotoxins of toxic, gram-negative bacteria. We chose this lipid due to it’s toxicity and unique, simplistic name. Docosahexaenoic Acid (DHA) DHA is a lipid that acts as a structural component of the nervous system and regulates the transport of neurotransmitters. It’s found in the

Water Desalination Everyone in this planet needs to be able to access water in order to live. 71% of the earth is covered by water, so accessing water from anywhere must be easy. However not all of the water on earth is freshwater. Only 3% of the world’s water is freshwater and ⅔ of the freshwater is tucked in glaciers. Everyone requires freshwater in order to live, as a result about 1.1 million people in this world lack access to freshwater. In India alone, only 18% of the population has access

Prokaryotic and eukaryotic cells must uphold an internal environment different than the outside in order to survive. The plasma membrane helps the cell achieve this. It is describe as a thin, flexible, oily sheet that puts a boundary between the cell and its environment. An important feature is that the membrane regulates movement of material in and out of the cell. While some cells can come and go as they want; others can only pass under certain conditions. A membrane is called fluid mosaic because

hydrophobic regions. Hydrophilic means that a substance loves water. The head of the phospholipid faces towards the water inside/outside of the cell. The middle layer of the membrane consists of the hydrophobic region. They form the lipid tails and they hate water. Since lipids and water does not mix well together, the middle of the phospholipid bilayer does not allow water to go inside. 2. An amphipathic molecule has both a hydrophilic and hydrophobic region. It refers to the “personality” of the molecule

cell membrane is largely a lipid? The cystol and all parts of the cell are made up of very polar; water-soluble molecules, which are hydrophilic “water loving”. The environment outside the cell is also very polar and water-soluble. In order to have an appropriate barrier between the inside of the cell and the outside, The membrane of the cell needs to be made of highly non-polar, organic material like lipids. The reason is because non-polar, organic matter like lipids and carbohydrates are very hydrophobic

on my model: The cell membrane is made up of a phospholipid bilayer. The membrane excludes, takes in, and excretes various substances, all in specific amounts. In addition, they must able to communicate with other cells. The plasma membrane needs lipids, which make a semi-permeable barrier between the cell and its environment. It also needs proteins, which are involved in cross-membrane transport and cell communication. Nucleus- the swirled light blue ball in the center of my model: The Nucleus

transduction, cell-cell recognition, intercellular joining and attachment to the cytoskeleton and extracellular matrix (ECM). Some membrane proteins span the membrane to provide a hydrophilic channel for hydrophilic substances to be able to pass through the lipid bilayer while other transport proteins are able to change their shapes to help move specific substances from one side to the other; some proteins use ATP as an energy source to actively move substances from one side of the membrane to the other. Some

Describe the importance of cell membrane, its structure and function Cells are the main components of organization in biology. All cells are surrounded by a cell membrane. The cell membrane is semipermeable; made of smaller molecules that form a porous and flexible composition. The cell membrane is made up of phospholipids that contain a hydrophilic head and a hydrophobic tail. Cholesterol stiffens the membrane by connecting the phospholipids together. Glycolipids signal other molecules and glycoproteins

Discuss the role of proteins in cell membrane transport Cell membranes are the barriers and gatekeepers of the cell; they provide overall structure, control the exchange of molecules between the extra and intercellular environments and are the site for many important processes. Cell membranes consist of a phospholipid bilayer where each repeating unit is comprised of two fatty acid tails bound to a phosphate head including a polar group attached to the glycerol region. Due to the amphipathic nature

is a bilayer. This experiment can be summarized in three steps. 1. They purified membrane lipids from red blood cell (they chose these because they have lack internal membranes). They estimated the number of starting cells and the surface area of each cell. This allowed the two scientists to calculate the total area of the membrane they purified. 2. They then dissolved the erythrocyte (red blood cell) lipids in benzene. From here they evaporated the benzene

All cells contain a semipermeable membrane that allows certain materials to flow through it according to the need of the cell (Biology 105: Laboratory Manual, 2017). The membranes are made of lipids and proteins that allow different sized molecules to pass through. Some molecules use passive transport, which requires no energy, to pass through the membrane. The molecules that do require energy go through the process called active transport. Active transport is made possible through ATP which is produced

“Oh la la la …..bebe on board??? …. Dance your way thro’ pregnancy”. Dancing & Pregnancy. “Dance ,when you’re are broken open. Dance ,if you’ve torn the bandage off. Dance in the middle of fighting. Dance in your blood, Dance when you’re perfectly free” This was said by Maulana Jalal al – Din Rumi (Rumi), a 13th century Persian poet, Islamic Jurist and theologian. When I read this quote, I was reminded of an advertisement that I came across stating “Belly dancing classes” for Pregnant women and

A: Phospholipid A1: Phosphate head (hydrophilic, polar) A2: Two fatty acid tails (hydrophobic, non-polar) B: Glycolipid C: Glycoprotein D: Carbohydrate E: Cholesterol F: Integral Membrane Protein G: Channel Protein H-I: Phospholipid Bi-layer (b) Explain how the properties of molecules A and C cause them to be arranged as shown in the plasma membrane. • When in water the phospholipid (A) is arranged in that particular manner because there are two layers of phospholipids aligned straight. The phosphate

communicate. Transport proteins allow certain molecules through the membrane. Glycoprotein are made of sugar and protein and they help with cell to cell communication and transport across membranes. These can be classified as peripheral, integral and lipid bound. Peripheral proteins sit on top of the phospholipids.