Basic pharmacology of agent used in the treatment of asthma Pharmacodynamics about Salbutamol (INN) or albuterol (USAN), a moderately selective beta (2)-receptor agonist similar in structure to terbutaline, is widely used as a bronchodilator to manage asthma and other chronic obstructive airway diseases. The R-isomer, levalbuterol, is responsible for bronchodilation while the S-isomer increases bronchial reactivity. The R-enantiomer is sold in its pure form as Levalbuterol. The manufacturer of levalbuterol
People who have been diagnosed with asthma need to take long-term control medication. These medications reduce airway inflammation and help prevent symptoms from occurring. An inhaled corticosteroid, is an anti-inflammatory drug that prevents cells in the lungs from releasing the substances that trigger the asthma response. Medications in this class are Flovent, Pulmicort, Aerobid, Alvesco, Qvar, and Asthmanex. A common side effect of these medications is a mouth infection referred to as thrush
Salbutamol undergoes considerable presystemic metabolism in the intestinal mucosa (sulphation) and hepatic conjugation to form an inactive metabolite that is excreted in the urine. Most (approximately 90%) of the dose administered by aerosol is swallowed, but the 10–15% which is inhaled largely remains as free drug in the airways. The plasma elimination half-life (t1/2) is two to four hours. Salmeterol is long acting, with a duration of action of at least 12 hours, allowing twice daily administration
Elliott Cole Mr. Jason Long, Instructor EMS Academy 20 January 2016 Anaphylactic Shock Anaphylactic shock and Anaphylaxis are serious medical conditions that are a result of insufficient blood flow throughout the body. Anaphylactic shock refers to severe hypersensitivity or an allergic reaction. Causes of Anaphylaxis often include allergic reaction to foods, medications, or insect stings. Anaphylactic shock on the other hand, is a medical emergency which can lead to other conditions such as a lack
2012). An anticholinergic nebulizer, ipratropium was given to mrs.Smith as per the order which helped to reduce dyspnea and cough slightly. Her Early warning score still remains 6. On detailed examination, Ed doctor suspected mrs.Smith may be having heart failure. ECG done on her which shows sinus
together. For example, in the case of Asthma. In the respiratory tract, albuterol will stick to the adrenergic receptors so the smooth muscle will relax and expand the airways, also known as bronchodilation. At the same time, the antagonist drugs, ipratropium, attaches to cholinergic receptors and obstruct the attachment of acetylcholine and limit the airways which called bronchoconstriction. Both of these drugs help to breathing easier but in the different
hypertrophy alone. However, if a CT scan of the head, facial bones, or sinuses has been obtained for other reasons, it may provide useful information. Axial and particularly coronal images can help assess the amount of bony versus mucosal hypertrophy. If clinical presentation raises the concern of other obstructive processes such as nasal polyps or masses, CT imaging of the nose and sinuses should be performed. Rhinomanometry: Rhinomanometry is a technique for measuring nasal airway resistance. It
Best Medicine for Runny Nose What is the best medicine for runny nose? Almost everyone experiences this annoying problem, and whether you are a child in school or a businessman at work, you will find it difficult to go through the day with this burden. The most common cause of excess drainage from your nose is a common cold, but you can also have one when you have allergies or a sinus infection. A runny nose is sometimes accompanied by cough, headache and earache, depending on the underlying cause