2. RESEARCH QUESTIONS: 1. What are the different forms of loneliness and alienation? 2. What are the factors that led to a sense of loneliness and alienation? 3. What are the effects of loneliness and alienation? 4. How do lonely and alienated individuals approach life? 5. How do individuals cope up with loneliness and alienation? 6. To what degree can one withstand the effects of loneliness and alienation? 3. RESEARCH OBJECTIVES: • To determine the causes and types of loneliness and alienation
a non purine compound and selective inhibitor of xanthine oxidase that has been developed for the treatment of hyperurecemia and gout. It has been found to have inhibitory activity for xanthine oxidase(XO)/xanthine dehydrogenase(XDH) during evaluation of a range of newly synthesized molecules. In humans, the xanthine oxidoreductase enzyme(XOR) catalyzes the last 2 steps in uric acid synthesis,the oxidation of hypoxanthine to xanthine and xanthine to uric acid. febuxostat was shown to inhibit both
Enzymes are giant molecular biological catalyst.They are responsible for thousands of metabolic processes that systain life.Enzymes are highly selective greatly accelerating both the rate and specificity of of metabolic reactions from the digestion of food to the synthesis of DNA..Most enzymes are proteins.They possesses a three-dimensional structure. Enzymes act by converting a starting molecule called as substrate into different molecules called as products.Almost all chemical rection in an biological
Question 2 - Inosine in AMP catabolism Introduction Adenosine monophosphate (from now on referred to as AMP) is the lowest energy-containing nucleotide found in living organisms. In its degradation process (Figure 1), several enzymes and intermediates are required, playing important roles that regulate the correct functioning of the overall process. An alteration in any of those participants can cause severe consequences, such as immunosuppression. Inosine is one of those previously mentioned intermediates
An enzyme can be regarded as a catalyst for a biochemical reaction, or more simply, a biological catalyst. Its sole purpose is to increase the rate of a reaction, or speed up the reaction via provision of an alternative reactive pathway, which entails a lower activation energy. Enzymes participate in the reaction itself, enabling the occurrence of an alternate pathways of reaction, but they do not attain permanent changes to their structure or nature, and as a result remain unchanged preceding a
1. Introduction Caffeine (1, 3, 7-trimethylxantheine) is a xanthine derivative and member of a class of drugs known as methylxanthines (Sutor, 1958). Caffeine is a plant alkaloid and was isolated from plants as a white crystalline substance for the first time in 1820 by Ferdinand Runge. Simillar compound was isolated from tea (Camellia sinensis) in 1827 by Oudry. However, in 1832 Pfaff and Liebig identify caffeine as a purine compound, and IUPAC name 1,3,7-trimethylxanthine was denominated (Mazzafera
Topic: People should not drink cow’s milk Thesis Statement: We should not drink cow’s milk as the cow’s milk may not good for our bones, causing heart disease and contributes to digestive problems. Milk is an opaque white fluid rich in fat and protein, secreted by female mammals for the nourishment of their young. There are many types of milk that we are aware to. The first ever milk that we consumed right after we were born is breast milk. But as we grow up, we were introduced to many types of
well-known tumor promoter, initiates oxidative stress (Wei H. et al.1993). Application of tocopherol to the skin 30 min before treatment with 12-O-tetradecanoylphorbol-13-acetic acid inhibits the production of H2O2, myeloperoxidase movement, xanthine oxidase action, and lipid peroxidation (Rahman S. et al. 2008). α-Tocopherol acetic acid suppress UVB-incited edema, erythema, and lipid peroxidation. UVA drastically up regulates the production of IL-8 mRNA and the secetion of IL-8 protein, and improves
Steven Johnson and toxic Epidermal Necrolysis the over lapping syndrome Steven Johnson Syndrome and toxic Epidermal Necrolysis SJS is also known as Steven Johnson Syndrome it is one of the rarest and painful skin disorder anyone can encounter it is mainly triggered by Drugs and medications. The diagnosis is suspected clinically and classified based on the skin surface area detached at maximum extent. This syndrome attacks the skins and mucosa membranes in the following ways. The skin