Clinical Trials Importance

Clinical Trials and Its Importance in Drug Discovery Introduction

Clinical trials are research studies that check how well new medical approaches work in individuals. Every study answers scientific queries and tries to search out higher ways to prevent, screen for, diagnose, or treat a disease. Clinical trials may additionally compare a brand new treatment to a treatment that 's already on the market.

Every clinical test incorporates a protocol, or action plan, for conducting the trial. The plan describes what will be done in the study, how it 'll be conducted, and why every a part of the study is critical. Every study has its own rules regarding who will participate. Some studies want volunteers with a particular disease. Some want healthy

Many different groups, companies, and organizations also sponsor clinical trials. Examples include Government Agencies, like the U.S. Departments of Defense and Veterans Affairs; private companies; universities; and nonprofit organizations. NIH Institutes and Centers (including the NHLBI) usually sponsor trials that test principles or methods. For instance, one NHLBI study explored whether the benefits of lowering high blood pressure in the elderly outweighed the risks. (NIH: National Institutes of Health)

In INDIA the Clinical Trials Registry- India (CTRI), hosted at the ICMR 's National Institute of Medical Statistics, is a free and on-line public record system for registration of clinical trials being conducted in India that was launched on 20th July 2007. Initiated as a voluntary measure, since 15th June 2009, trial registration within the CTRI has been made mandatory by the medicine Controller General (India) (DCGI). Moreover, Editors of biomedical Journals of eleven major journals of India declared that only registered trials would be considered for

Clinical research informs clinical practice and evidence based medicine. Preapproval clinical trials bring new drugs to market and provide the information contained within each drug’s prescribing information (label). This information concerning the drug’s safety and therapeutic benefit, which is the best available information at the time of approval, guides treatment decisions at the individual patient level. Clinical trials also generate the evidence contained within treatment practice guidelines, which have a broader reach across populations of patients. Clinical trials conducted after the drug’s approval, along with spontaneous safety reporting and active post marketing surveillance, provide additional information that may lead to changes to the drug’s label over time as the drug’s use in clinical practice increases. This paper provides an overview of clinical trial categorization in new drug