It is also a gram positive. It is used to contaminant the sick patients as it resistant by slowing a major processes of metabolic and induction of unique genes. Mezlocillin: Mezlocillin is a broad- spectrum penicillin antibiotic. This penicillin have higher chance against gram negative and some on gram positive bacteria.But it is excreted by liver, that why it is useful for treating biliary tract infections, such as ascending cholangitis. Cefazolin:An antibiotic which will work on many bacteria infection.It normally administered either by intravenous infusion ( intravenous fluid into vein) or intramuscular injection (injection into a large muscle).As many of the antibiotics it also have side effect which are vomiting,diarrhea,nausea, and rash.
Nitroimidazo oxaine is also active against latent TB bacteria .In a latent state, bacteria are anaerobic and else replicating very slowly and non replicating. In 2008 researchers from the national Institute of allergy and Infectious Diseases found that Nitroimizado oxaine kills latent bacteria by releasing a gas called nitric oxide , which poisons the bacteria . Nitroimizado oxaine mimics the body’s natural immune response ,but it is more specific and only releases the gas upon entering the tuberculosis
Ionization refers to the production of gas phase ions suitable for resolution in the mass analyser or mass filter. There are a many on sources available, each has advantages and disadvantages for particular applications. For example, Electron Ionization (EI) gives a high degree of fragmentation, yielding highly detailed mass spectra which when skilfully analyzed can provide important information about structural elucidation/characterization and facilitate identification of unknown compounds by comparison to mass spectral libraries. However, EI is not suitable for coupling to High-performance liquid chromatography, since at atmospheric pressure, the filaments used to generate electrons burn out rapidly. Thus EI is coupled predominantly with Gas Chromatography, where the entire system is under high
But it was formerly known as High Pressure Liquid Chromatography. HPLC is an instrumental system to perform the technique of analytic chemistry to separate the chemical or biological compounds which are non-volatile and thermally-unstable such as pharmaceutical products, organic compounds, food and beverages, natural products and others. HPLC can be used in many fields. As examples, HPLC can be used in medical field to detect the concentration of antibiotics or vitamins levels in blood serum. HPLC also make its contribution to pharmaceutical manufacturer.
This derivative exhibited maximum fluorescence intensity at 540 nm after excitation at 476 nm (Figure 2), the maximum absorbance of the reaction product was measured at 480 nm (Figure 3). 3.1. Optimization of the reaction conditions The experimental parameters affecting the development and stability of the reaction product between the drug and the reagent were investigated and optimized. Each parameter was changed individually while the others were kept constant. These parameters include; pH, buffer (type & volume), concentration of NBD-Cl, reaction and stability time, temperature, acidification and diluting solvent.
Conclusion The proposed HPLC method provides simple, accurate and reproducible quantitative analysis for simultaneous determination of atenolol and pregabalin in dosage forms, spiked and human urine. The cumulative excretion patterns of atenolol and pregabalin have a valuable clinical application by detecting the concentration of the two drugs in urine at any time during 24 hours after oral
Flucloxacillin: - It is a member of the penicillin family that is used as an antibiotic for the staphylococcal infection (bacterial infection) that affects the human tissues of the skin and the lungs (pneumonia). It is also used in the treatment of food (rotten food) and poisoning of theblood. Staphylococcus may also be a risk to the human life if it releases its toxins by some strains of the bacteria to cause toxic shock. - Flucloxacillin is prescribed mainly in Australia & Europe, as it is very effective against the staphylococcus bacteria by inhibiting the synthesis of its cell wall then it will die. - Flucloxacillin is a ß-lactam antibiotic with a narrow spectrum.
The following best-studied species are P. aeruginosa; there is an opportunistic human pathogen. This implies that the organism causes illness once a person’s immune system is already impaired. Members of the genus show these clarify characteristics (Euzéby, 1997). Pseudomonas is rod-shaped, flagellum one or more, providing motility. It is Aerobic, Non-spore forming, Catalase-positive and Oxidase-positive.
The two most potent classes of antibiotic are the macrolides (azithromycin), and the quinolones (ciprofloxacin, levofloxacin, moxifloxacin, gemifloxacin, trovofloxacin). Other agents that have been shown to be effective include tetracycline, doxycycline, minocycline, and trimethoprim/sulfamethoxazole. Erythromycin, the former antibiotic of choice, has been replaced by more potent and less toxic antibiotics. There are three major classes of antibiotics that are effective in treating legionellosis. These include the fluoroquinolones such as levofloxacin (Levaquin), and moxifloxacin (Avelox), the macrolides such as erythromycin, azithromyocin (Zithromax), and clarithromycin (Biaxin), and the tetracyclines including doxycycline (Vibramycin).
DMSO is a potent scavenger of the free radical but maintaining normal integrity of cells and tissues. DMSO acts as synergistic drug with other therapeutic agents [Dake1967]. DMSO is bacteriostatic in 20% concentration against Escherichia coli, Staphylococcus sp and