Pyelonephritis Research Paper

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Pyelonephritis is a kidney infection of a causative agent such as bacteria called Escherichia coli (E. coli). Transmission is due to poor hygiene or an untreated urinary tract infection (UTI). A basic description of pyelonephritis is inflammation of the kidneys due to an infection of the renal pelvis and is sometimes asymptomatic. This infection can destroy the structures of the kidney such as the loop of Henle, nephrons, and corpuscles all important for the kidney to concentrate urine. Antibiotics are used for treatment, however it depends on the causative agent. Surgery, dialysis, or nephrectomy may be considered for Chronic pyelonephritis. Acute pyelonephritis: The systemic symptoms are fever, chills, back pain, and nausea and vomiting. The need to urinate along with burning and pain, including the smell and the color of the individual are symptoms. In chronic pyelonephritis, the symptoms are as follows: anemia, weakness, hypertension, and loss of appetite. A healthy kidney has over a million nephrons. The nephron is a tubular network that blood delivers fluid to. These nephrons are constantly filtering the blood from…show more content…
In obstructive Chronic Pyelonephritis, the kidney walls become thin and the scarring can be seen from the cortex to the medulla Vesicoureteral reflux (VUR) is the failure of the vesicoureteral orifice that can be the result of bladder outlet obstruction (BOO) increasing pressure on the bladder distorting the valve. This means that urine is able to move back into the kidney because of the failure of the vesicoureteral orifice valve. In a healthy kidney, the flow of urine descends from the kidney to the ureter into the bladder. The valve closes after urine flows into the bladder. However, in regard to pyelonephritis, the valve is distorted due to VUR allowing the flow of urine to ascend back into the ureter and the

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