Within the first three days of wound repair, basic FGF from macrophages initiate angiogenesis and the subsequent injury–induced hypoxia stimulates the production of VEGF by epidermal cells followed, which sustained the angiogenesis stimulus for the next four days. Next, both plasmin and collagenase works synergistically to digest basement membranes so as to allow endothelial cells to migrate and form new blood vessels at the injured site. Once the wound is filled with new granulation tissue, angiogenesis ceases and many of the new blood vessels undergo apoptosis. On a similar note, there is continued growth of damage blood
Within the first three days of wound repair, basic FGF from macrophages initiate angiogenesis and the subsequent injury–induced hypoxia stimulates the production of VEGF by epidermal cells. VEGF sustains the angiogenesis stimulus for the next four days. Next, both plasmin and collagenase works synergistically to digest basement membranes so as to allow the endothelial cells to migrate and form new blood vessels at the injured site. Once the wound is filled with new granulation tissues, angiogenesis ceases and many of the new blood vessels undergo apoptosis. On a similar note, there is continued growth of damage blood
An open fracture is a broken bone that penetrates the skin. Compared to a broken bone that does not pierce the skin (a closed fracture), an open fracture increases your risk for infection. Therefore, immediate treatment is necessary. This often requires an operation to clean the affected area to prevent infection. Furthermore,
Usually when somebody has a heart attack, people sometimes wait a while before seeking the much needed medical attention. It is extremely important that the patients gets medical treatment as soon as possible after the occurrence of the myocardial infarction as this increases the chances of their survival. CAUSES Myocardial infarction is usually caused by a blockade in the blood supply of the heart muscles. This can occur when there is the hardening of the arterial walls, or if there is an thrombus or embolism in the blood vessels and this reduces the amount of blood that can go through. If there is a complete block, then this can cause the area where the blood vessel supplies the blood to undergo necrosis which is also known as heart attack.
On the other hand, the patient’s systolic blood pressure may rise during surgery and conventional tourniquet systems which remain on the initial setting pressure throughout the procedure cannot respond to these hemodynamic changes. In this case, the inflation pressure should be adjusted manually in order to prevent oozing from an increase in systolic blood pressure or not to apply unnecessary high inflation pressures from a decrease in systolic blood pressure. Since this needs an additional time and work for the personnel, a fixed safety margin of 100-150 mmHg has been suggested to add the patient’s
Intestinal ischemia Overview: Intestinal ischemia occurs when the blood vessels that flow bowel contract or block, thereby reducing the blood supply. Ischemia can affect the small intestine or colon, or both. The reduction in blood flow can cause pain and provide permanent injury to the bowel. The acute intestinal ischemia, or quickly stopping the direct circulation to the intestine, is an emergency and requires immediate surgery; that chronic, manifested in time, but must be treated because it can turn into acute or cause severe weight loss and malnutrition. Causes: The intestinal ischemia occurs when the direct circulation to the intestine decreases or stops completely.
Of course there are complications if it is not treated quickly, because we all know that we can avoid financial problems in this life. COMPLICATIONS : • Tears in the wall and rupture of the aorta are the main complication of thoracic aortic aneurysm. A ruptured aneurysm is so dangerous that some people can die because of the internal bleeding. • Trouble swallowing, Loss of consciousness, low blood pressure, trouble breathing, pain at the back, intense chest pain, shortness of breath, low blood pressure and weakness or paralysis of one side of the body sometimes the other sign for Stroke, are the symptoms that your thoracic aortic aneurysm has
diagnosis of deadly diseases) until the occurrence of a specific event (i.e. death) or endpoint . Survival analysis is called reliability analysis in engineering, duration analysis in economics, event history analysis in sociology and medical researchers give it the name of survival analysis. Survival analysis is used because the survival data are generally not symmetrically distributed, so it can not follow the normal distribution. The survival data depend on the time and it render standard methods in which the survival times are frequently censored .
The loose blood clots can block the artery in the heart and become pulmonary embolism (PE). A pulmonary embolism is dangerous conditions that can lead to fatal because of blood supplies from the heart to the other parts of the body are failed. DISEASE CLASSIFICATION Deep vein thrombosis can be classified to three categories which is idiopathic, acute and chronic. Idiopathic deep vein thrombosis can characterized with usual condition acquired risk factors, such as obesity, trauma, cancer, or surgery. Acute deep vein thrombosis can be seen by pain and swelling.
Subacute subdural hematoma of the left hemisphere with subacute subdural hematoma midline moving from right hemisphere Chronic subdural hematoma constitutes slowly over a period of several weeks, sometimes months, following a minor trauma that may go unnoticed. Chronic subdural hematoma chronic subdural hematoma Extradural hematomas usually occur secondary fractures and blood collection is located between the skull and the outer skins covering the brain (dura). Extradural hematoma extraduralHematom Head trauma is associated with a high proportion of other organ trauma and limb therefore trauma patient must receive care and treatment in a specialized center capable of providing intensive care to critically ill patients and treatment appropriate surgical, orthopedic, thoracic surgery, plastic and reconstructive surgery, etc. Treatment: In case of loss of consciousness, the patient must first be stabilized in terms of breathing (airway), the blood circulation (stopping bleeding), then have stabilized neck (collar immobilization) and head. These maneuvers are usually at the crash site by trained personnel of salvation, before the patient to reach the