Plasmapheresis Essays

most serious complication is nephrotoxicity, which may result in irreversible renal failure. Key management strategies for a cisplatin overdose involve renal protection and enhancing drug elimination, and consideration of sodium thiosulfate and plasmapheresis. A suggested algorithmic approach for the initial management of a patient with a cisplatin over-dose is presented in figure 2. To our knowledge, patients inadvertently receiving less than 300 mg/ m2 of cisplatin reportedly often recover, whereas

based on four different options which take different amounts of time before muscular weakness will improve ,improvement of neuromuscular transmission by acetylcholine esterase inhibitors, e.g. pyridostigmine .treatment of acute exacerbations (plasmapheresis, immunoadsorption, intravenous immunoglobulin) • immunosuppression , thymectomy. but it can be treated with drugs, called anticholinesterases, that inhibit an enzyme, acetylcholinesterase, that breaks down acetylcholine in the body leads to increase

Myasthenia Gravis Myasthenia gravis is a disease that causes your muscles to tire easily and become weak. This condition affects the nerves that stimulate muscles to contract, with the muscles around the eyes being affected first. Myasthenia is not an inherited or contagious condition, but it commonly affects women under the age of 40 and men over age 60. Part 1: What Is Myasthenia Gravis? Every muscle receives nerve supply from nerves that split into smaller nerve fibers. These spread along the

the muscle weakness spread to my already strained breathing muscles, that I may need to be placed on a breathing tube. They treated me with plasmapheresis, a plasma exchange in which my blood was filtered through a machine, treated and then supplemented with a donor’s plasma before being returned to my body. After six sleepless nights and three plasmapheresis sessions, in which every subtle movement was met with a prickling, acute pain and in which every word I uttered was accompanied by a lisp courtesy

What is Multiple Sclerosis: Multiple Sclerosis is primarily a T-cell mediated immune inflammatory disease that disrupts the regular functions of our central nervous system. Our central nervous system, the brain and the spine, are responsible for many of our voluntary and involuntary movements. However, in patients with Multiple Sclerosis, the immune system attacks the myelin sheaths that protect the nerves of the CNS. After repeated attacks, the myelin sheath will fall apart, and the immune cells

The first treatment is called plasma exchange or plasmapheresis. A liquid portion from the blood called plasma is removed and separated from the blood cells. The plasma is then brought back into the body, which produces more plasma that was taken away by the attacking immune system. This treatment may even

Steven Johnson and toxic Epidermal Necrolysis the over lapping syndrome Steven Johnson Syndrome and toxic Epidermal Necrolysis SJS is also known as Steven Johnson Syndrome it is one of the rarest and painful skin disorder anyone can encounter it is mainly triggered by Drugs and medications. The diagnosis is suspected clinically and classified based on the skin surface area detached at maximum extent. This syndrome attacks the skins and mucosa membranes in the following ways. The skin

Guillain-Barré syndrome (GBS) is a disorder in which the body 's immune system attacks part of the peripheral nervous system. The first symptoms of this disorder include varying degrees of weakness or tingling sensations in the legs. In many instances the symmetrical weakness and abnormal sensations spread to the arms and upper body. These symptoms can increase in intensity until certain muscles cannot be used at all and/or the person is almost totally paralyzed. In some severe cases the disorder

Myasthenia gravis is a chronic autoimmune neuromuscular disease characterized by varying degrees of weakness of the skeletal muscles of the body. It occurs when communication between nerve cells and muscles becomes impaired. This impairment prevents crucial muscle contractions from occurring, resulting in muscle weakness. Normally when impulses travel down the nerve, the nerve endings release a neurotransmitter substance called acetylcholine. Acetylcholine travels from the neuromuscular junction

1. As states by Smith (2012), microcytic anemias are due to impaired hemoglobin production, either from ineffective heme or globin synthesis. The most common causes of decreased heme synthesis are iron deficiency (i.e., when iron loss exceeds intake) and chronic disorders (i.e., infectious, inflammatory or cancerous disorders that impair the utilization of iron). Regardless of the cause, the inhibition of heme synthesis results in erythrocytes that are smaller and contain a lower concentration of

into a large vein to obtain an intravenous access. Its use has become indispensable in the management of critically ill patients. Central venous catheters are used for hemodynamic monitoring, measurement of Central Venous Pressure, hemodialysis / plasmapheresis and in setting of difficult peripheral venous access in critically ill patients. Despite its benefits, central venous catheters have drawbacks as well. Insertion of central venous catheters can be associated with mechanical complications like

hypertension, urinary tract infections, vesicoureteral reflux, renal tubular disorders, kidney stone, acute and chronic renal failure. Procedures done at our Centre: 1. Renal Biopsy 2. Acute and Chronic Peritoneal dialysis 3. Hemodialysis 4. Plasmapheresis Presentation of a child with kidney disease Kidney disease in children often remain undiagnosed due to non specific signs and symptoms. The tell

Question 4 Answer: Dopamine, norepinephrine, and epinephrine are a group of neurotransmitters called catecholamines. Catecholamines are synthesized from tyrosine, an amino acid (1). Structurally, “they all have an amino group (—NH2—NH2) and a catechol ring composed of six carbons and two adjacent hydroxyl (—OH—OH) groups” (1). These catecholamines, “may cause either excitation or inhibition, depending on the type of metabotropic receptor at the synapse” (1). Norepinephrine is produced in the adrenal