The Controversies of Gene Editing Technology
The ability to edit genes is a widely disputed and controversial topic, resulting in many varied opinions between scientists and scholars. It is argued whether or not gene editing technology is safe for all participants, as well as if it is ethical. Some scientists believe that gene editing technology is the next step in evolution of certain science processes, and the future of curing and preventing genetic diseases. Others, however believe, that if gene editing technology is taken too far, it will go beyond the prevention of genetic diseases, allow the creation “perfect” children. The opinions on gene editing technology are varied, and shown through the content and research of this paper. Gene
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As of 2014, forty countries have banned genome editing. One concern is a safety issue, with the possibility of off-target effects, or edits in the wrong places, along with mosaicism (when some cells carry the genetic edit, but others do not. Also, many people do not support the genetic-editing of human embryos due to moral and religious values. Changes created in a human embryo by gene-editing technology may be passed onto future generations, and “germline cell and embryo genome editing bring up a number of ethical challenges, including whether it would be permissible to use this technology to enhance normal human traits (such as height or intelligence). Based on concerns about ethics and safety, germline cell and embryo genome editing are currently illegal in many countries.”(ghr.nlm.nih.gov) In addition, the National Institute of Health (NIH) will not fund any use of gene-editing in human embryos, and federal funds cannot be used for any research that creates or destroys embryos. Some people also believe that although gene editing technology could prevent genetic diseases, it could be taken too far. This includes scientists using the concept of gene-editing technology to create “perfect children”. To conclude, there are many points on the con-side of gene-editing …show more content…
One argument states that gene-editing technology will be very beneficial to many people by eliminating genetic diseases. “Every year an estimated 7.9 million children - 6% of total births worldwide - are born with a serious birth defect of genetic or partially genetic origin.”(https://www.theguardian.com/science/2015/dec/02/why-human-gene-editing-must-not-be-stopped), “An estimated 3.3 million children under the age of 5 die each year from serious birth defects, a worldwide report says. But more effective interventions and the use of medical genetic services, especially in poorer countries, could reduce mortality and disability by up to 70%.” (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1360426/). The use of gene editing could prevent millions of people from having genetic diseases. Gene editing on human embryos can also lead to making disease treatment less expensive. Its could lead to a greater understanding of genetic diseases, and other disease treatments. The knowledge could allow many medicines to be produced more cheaply, allowing medicines to be accessible to more people. “Genetic engineering can be used to improve the drugs available on the marketplace by making them more effective and safer. By using genetic modification scientists can make pharmaceuticals more effective than the existing versions of the medicine. There are already improved versions of insulin for
Mankind has always been motivated by the desire for progress, accomplishment, and empowerment. The exceptionally steep rate of technological development during the twentieth century starting with the invention of the zeppelin in 1900 and advancing to the creation of more sophisticated technologies such as the world wide web is evidence of this truth. In the midst of all of these impressive innovations, biological scientists developed recombinant DNA techniques that gave them the power to alter genetic material. As biotechnology has become more refined and the application of genetic engineering in both agricultural and medical fields has become more common, the practice has fallen victim to harsh scientific and ethical scrutiny. The debate is
The issue of modification through gene manipulation becomes increasingly complex when considering how this technology can be used as a means to unethical and harmful uses. In the article, Babies with Genes From 3 people could be Ethical, Panel Says, Rob Stein exposes various concerns about three gene donors in an embryo, including how a scientist, “Could introduce some new disease into the human gene pool or that scientists could try to do this for other reasons-nonmedical reasons, like create designer babies where parents pick the traits of their children.” Stein goes on to explain how the gene replacement procedure would take place, which continues to usher in a plethora of concerns as whether to allow Crispr technology be tested on a embryo.
Human genetic modification is the manipulation of genes in human DNA so that defective genes don’t obstruct proper functioning, and so that inherited diseases are not passed on. Those against it may argue that genetic modification is simply unnecessary, immoral, or interferes with nature’s course. However, genetic modification overall is and will continue to be beneficial to the mental and physical health of the entire human species. Falling under the umbrella of biology, it is sensible to consider the studying of genes as a significant aspect of the biological sciences because it’s learning how to manipulate them in order to progress preventative medicine and create the possibility of a healthier future. One method of genetic modification
This type of gene editing has been tested for over twenty years, so it is well-researched and highly regulated. Somatic gene editing is used to treat or cure genetic diseases by making changes in the DNA of the targeted cells. This means changes are only made to the patient’s DNA because sperm or egg cells are not edited. To use somatic gene editing, some of the patient's stem cells are removed, CRISPR (or another gene editing technology) is used to correct the mutation, the corrected cells are infused back into the patient, and the corrected cells start replicating (Bergman). One study, conducted by Sikandar Hayat Khan, compared different gene editing technologies, which showed that the most efficient and practical gene editing technology is CRISPR/Cas9.
The Rise of Human Genetic Modification? There are many controversial issues throughout time that have risen and led countries to disagree to with one another worldwide. Eugenics and genetic engineering on humans is a topic that many believe crosses a major ethical boundary. Many scientists and ethicists believe that gene editing on human genes is unethical at certain degrees and it should not be done until the proper precautions have been overlooked and restrictions are made.
Finally, genetic modifying can allow people to live longer. You may think that this is good that people would live longer, but there some negative aspects to this. Life would be very boring of course, but more importantly, overpopulation would happen and humans would be in competition with one another since everything would now be limited. While some aspects of genetic engineering should appealing, they all most likely have a dark secret hiding within
In addition to helping unborn babies and ending hereditary diseases, gene editing can be used to cure and treat a variety of conditions and diseases. In society today, the population of developed countries is dying because of diseases like cancer and heart disease. Gene editing can modify different cells in the human body to attack cancer cells and heal damaged tissue. Recently, scientists used gene editing therapy to make a leukemia patient cancer-free. The researchers treated the patient by modifying her T cells into CAR T cells, which would track and destroy cancer cells.
This procedure’s purpose is to switch out genes for more preferred ones, especially to improve the health of the child. Genetic engineering could permit selection of desired physical and pleasurable traits for non-medical reasons, which has created concern in some people. The process of switching out the genes of a fetus to install genes that are more preferred has brought up debate about whether or not parents should be able to alter their babies genes to make them more appealing to the parents interests. There are many different ways of looking at this procedure and in contrast to other scientific procedures it can be for greater good or for unnecessary enhancement that could potentially create problems in society. Designer babies aren’t morally correct or incorrect, but are in between depending on what it is being used for.
Gene editing is the alteration of a person’s genetic material to delete undesirable traits or to create desirable new ones. Scientists can identify a defective DNA strand to be cut out and changed, then they use a protein that acts like scissors to cut out the improper gene and cells, then a healthy strand of DNA is inserted at the cut site and enzymes repair it (Crow). The goal of gene editing is to treat genetic disorders. Gene editing could potentially decrease or even
In conclusion, genetic engineering has plenty of benefits. Those benefits would be able to increase food production, eliminating diseases/disorders, and choosing the best traits in an
Recent developments in genome editing increased the scope of possibilities of genome editing; every part of the genome can efficiently, quickly and cheaply be altered. This potential increase in scope might have implications for the ethical issues related to genetic modified organisms (Newson and Wringley, 2015). Factually, genome-edited plants are GMOs, but they vary from cultivated GMO crops. The later have transgenes introduced from other organisms as well as species. By contrast, genome editing technology allows precise mutation of a specific endogenous gene, the alteration of current allele to a more favorable one, or the particular insertion of an identified variant into other breeds.
The websites both identify genome editing as a positive resource to edit multiple sites in a cell. However, there has been a large outburst of negativity surrounding this procedure within the past few years. Instead of addressing the ethnical issues that the public has with the genome editing technique, both articles choose to not incorporate the negative feedback that this procedure has been receiving. In its place, both articles use logos to address all the positives that genome editing has to offer. For example, in the last paragraph in the Nuffield Council on Bioethics, the author writes, “Given that genome editing has the potential to alter any DNA sequence…it has an almost limitless range of possible applications in living things” (Nuffield Council on Bioethics, 2016).
All humans have some genetic strains that end up causing problems or illnesses later on in life. Although we have not perfected this, there is a way to alter your genes to try and correct this faulty DNA; gene therapy. Problems that we face in today's society regarding health that could be remedied include: diabetes, AIDS, Alzheimer's, cancer, and even HIV. Thousands of people die from these illnesses, and gene therapy is a way to limit the casualties. Though, many people still find this practice unethical.
This essay will look more on the advantages and disadvantages of genetic engineering. Genetic engineering has some advantages. Firstly it allows for faster growth rate .Genetic engineering allows of plants or animals to be modified so their maturity can occur at a quicker pace outside of the normal growth conditions that are favourable without genetic changes as well .Secondly, it may also provide a cure for disease to improve health (apecsecadmin, 2014). Genetic engineering can be used to eradicate a number of incurable and deadly disease which could be done by identifying the genes that cause these disease, and manipulate them to prevent people from contracting these potentially deadly diseases.
“The main arguments against genetic modification of human embryos are that it would be unsafe and unfair, and that modification would quickly go beyond efforts to reduce the incidence of inherited maladies” (Caplan). During the altering genes in the mother 's womb cause a lot of dangerous situations and