Propionibacterium Acnes Lab Report

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Bioactivity guided fractionation of potent anti-acne plant extract against Propionibacterium acnes 1. Vinod Gauttam Department of Pharmacognosy, ISFcollege of Pharmacy, Moga, Punjab, India * vinodgauttam@gmail.com 2. Nitisha Negi Department of Pharmacognosy, ISFcollege of Pharmacy, Moga, Punjab, India * nitisha.negi@gmail.com 3. Malika Arora Department of Pharmaceutics, ISFcollege of Pharmacy, Moga, Punjab, India * maliksmonu@gmail.com 4. Kavita Munjal Department of Pharmacognosy, ISFcollege of Pharmacy, Moga, Punjab, India * kavitamunjal915@gmail.com ISF College of Pharmacy, Moga, Punjab, India ABSTRACT Background: Propionibacterium acnes (P. acnes) are a commensal anaerobic, Gram positive bacterium that belongs to the normal microflora. P. acnes plays an important role in the pathogenesis of various skin infections and diseases. But the available agents are associated with number of side effects and P. acnes show the genetic base of antibacterial resistance against erythromycin and clindamycin. Therefore, alternative natural approaches for the treatment are needed for alleviation of infection caused by P. acnes. Objective: To find out the most effective anti P. acne extract amongst the selected four plants, commonly used for anti-acne potential and to obtain the characterized fraction of the extract with highest anti P. acne potential. Method:…show more content…
S.K. Srivastava, Scientist D/HOO, Botanical Survey of India (B.S.I), Dehradun (Ref. No. BSI/NRC/TECH (Ident.)/2013-2014/ 1032). The Tephrosia purpurea (leaves) were procured from Tirupati, Andhra Pradesh and authenticated by Dr. K. Madhava Chetty, Associate Professor, Department of Botany, Sri Venkateshwara University, Tirupati, Andhra Pradesh,

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